(Q27551750)

English

Tho2p YNL139C

fungal protein found in Saccharomyces cerevisiae S288c

Tho2p
YNL139C
THO2

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

10 December 2016

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleic acid binding

determination method

1 reference

8 April 2019

The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

protein binding

determination method

6 references

5 June 2018

TREX is a conserved complex coupling transcription with messenger RNA export

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

5 June 2018

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

5 June 2018

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

5 June 2018

Proteome survey reveals modularity of the yeast cell machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

5 June 2018

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

5 June 2018

High-definition macromolecular composition of yeast RNA-processing complexes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

determination method

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

determination method

1 reference

8 April 2019

The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

nucleoplasmic THO complex

determination method

THO complex part of transcription export complex

determination method

1 reference

16 July 2018

TREX is a conserved complex coupling transcription with messenger RNA export

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

8 April 2019

A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

8 April 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

nucleoplasmic THO complex

determination method

1 reference

8 April 2019

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

biological process

transcription elongation from RNA polymerase II promoter

determination method

mRNA 3'-end processing

determination method

1 reference

8 April 2019

Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

mRNA export from nucleus

determination method

1 reference

16 July 2018

TREX is a conserved complex coupling transcription with messenger RNA export

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

regulation of transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53552&geneProductId=UniProtKB:P53552

determination method

DNA recombination

determination method

1 reference

8 April 2019

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

transcription-coupled nucleotide-excision repair

determination method

1 reference

8 April 2019

A new connection of mRNP biogenesis and export with transcription-coupled repair

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

positive regulation of transcription by RNA polymerase I

determination method

1 reference

8 April 2019

The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

positive regulation of transcription elongation from RNA polymerase I promoter

determination method

1 reference

8 April 2019

The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

stress granule assembly

determination method

1 reference

8 April 2019

Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

mRNA processing

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

mRNA export from nucleus

determination method

3 references

8 April 2019

TREX is a conserved complex coupling transcription with messenger RNA export

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53552

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

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