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CCR4-NOT core subunit CDC36 YDL165W
fungal protein found in Saccharomyces cerevisiae S288c
CCR4-NOT core subunit CDC36
CDC36
YDL165W
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P06100
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
851389
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P06100
encoded by
CDC36
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P06100
molecular function
ubiquitin-protein transferase activity
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
protein binding
determination method
IPI
4 references
retrieved
9 May 2019
stated in
Functional organization of the yeast proteome by systematic analysis of protein complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IPI
retrieved
9 May 2019
stated in
Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IPI
retrieved
9 May 2019
stated in
An in vivo map of the yeast protein interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IPI
cell component
P-body
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06100&geneProductId=UniProtKB:P06100
determination method
IBA
cytoplasm
determination method
IEA
IDA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06100
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IEA
retrieved
9 May 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IDA
nucleus
determination method
IEA
IDA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06100
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IEA
retrieved
9 May 2019
stated in
NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IDA
CCR4-NOT core complex
determination method
IPI
1 reference
retrieved
27 March 2018
stated in
The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06100&geneProductId=UniProtKB:P06100
determination method
IPI
CCR4-NOT core complex
determination method
IEA
IPI
2 references
retrieved
9 May 2019
stated in
The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IPI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IEA
biological process
deadenylation-independent decapping of nuclear-transcribed mRNA
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
negative regulation of translation
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06100&geneProductId=UniProtKB:P06100
determination method
IBA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P06100
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06100&geneProductId=UniProtKB:P06100
determination method
IEA
deadenylation-dependent decapping of nuclear-transcribed mRNA
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
response to pheromone triggering conjugation with cellular fusion
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Mutations in cell division cycle genes CDC36 and CDC39 activate the Saccharomyces cerevisiae mating pheromone response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
determination method
IMP
IDA
IGI
3 references
retrieved
14 February 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
retrieved
14 February 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IGI
retrieved
14 February 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IDA
nuclear-transcribed mRNA poly(A) tail shortening
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IDA
transcription elongation from RNA polymerase II promoter
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
regulation of transcription by RNA polymerase II
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IPI
positive regulation of transcription elongation from RNA polymerase II promoter
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
The multifunctional Ccr4-Not complex directly promotes transcription elongation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IDA
regulation of cell cycle
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Mutations in cell division cycle genes CDC36 and CDC39 activate the Saccharomyces cerevisiae mating pheromone response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
protein ubiquitination
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IEA
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IMP
retrieved
9 May 2019
stated in
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06100
determination method
IDA
Identifiers
RefSeq protein ID
NP_010116
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
851389
UniProt protein ID
P06100
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P06100
Ensembl protein ID
YDL165W
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YDL165W
Saccharomyces Genome Database ID
S000002324
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
851389
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