(Q27552780)

English

Ste5p YDR103W

fungal protein found in Saccharomyces cerevisiae S288c

STE5
YDR103W
Ste5p

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

10 December 2016

Ste5, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32917

Protein Ste5, Fus3-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Scaffold protein Ste5, Fus3-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

phosphatidylinositol-4,5-bisphosphate binding

determination method

1 reference

14 February 2019

Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

protein binding

determination method

9 references

14 February 2019

Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

Recognition of non-canonical peptides by the yeast Fus1p SH3 domain: elucidation of a common mechanism for diverse SH3 domain specificities

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

Fus1p interacts with components of the Hog1p mitogen-activated protein kinase and Cdc42p morphogenesis signaling pathways to control cell fusion during yeast mating

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

Exploitation of latent allostery enables the evolution of new modes of MAP kinase regulation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

14 February 2019

The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

G-protein beta-subunit binding

determination method

1 reference

14 February 2019

Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

MAP-kinase scaffold activity

determination method

determination method

1 reference

14 February 2019

Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

mating projection tip

determination method

plasma membrane

determination method

1 reference

14 February 2019

Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

mating projection tip membrane

determination method

1 reference

14 February 2019

Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

biological process

regulation of transposition, RNA-mediated

determination method

1 reference

14 February 2019

Posttranslational regulation of Ty1 retrotransposition by mitogen-activated protein kinase Fus3

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

pheromone-dependent signal transduction involved in conjugation with cellular fusion

determination method

response to pheromone

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

positive regulation of protein phosphorylation

determination method

1 reference

14 February 2019

The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

invasive growth in response to glucose limitation

determination method

1 reference

14 February 2019

Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

negative regulation of MAPK cascade

determination method

1 reference

14 February 2019

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

positive regulation of MAPK cascade

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32917

determination method

Scaffold protein Ste5, Fus3-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32917

Protein Ste5, Fus3-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32917

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Sitelinks

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Multilingual sites(0 entries)

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