(Q27619063)

English

Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase

scientific article

Crystal Structures of Zinc-free and -bound Heme Domain of Human Inducible Nitric-oxide Synthase

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scholarly article

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Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase (English)

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crystal structure

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author name string

H Li

1

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C S Raman

2

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C B Glaser

3

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E Blasko

4

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T A Young

5

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J F Parkinson

6

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M Whitlow

7

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T L Poulos

8

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language of work or name

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publication date

23 July 1999

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Journal of Biological Chemistry

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274

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21276-84

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30

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Nitric oxide synthases in mammals

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Nitric oxide synthases: properties and catalytic mechanism

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Natural resistance and nitric oxide

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

AMoRe: an automated package for molecular replacement

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Solvent content of protein crystals

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

The CCP4 suite: programs for protein crystallography

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49 amino acid segment required for subunit dimerization and tetrahydrobiopterin interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Endothelial nitric oxide synthase: modulations of the distal heme site produced by progressive N-terminal deletions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

The molecular surface package

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Zinc mining for protein domains

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Inhibition of nitric oxide synthase activity by Zn2+ ion.

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

The activation of eNOS by copper ion (Cu2+) in human pulmonary arterial endothelial cells (HPAEC).

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Domains of macrophage N(O) synthase have divergent roles in forming and stabilizing the active dimeric enzyme

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

The nucleotide sequence of the initiator tRNA from Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Protein-protein interactions: a review of protein dimer structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Subunit interactions of endothelial nitric-oxide synthase. Comparisons to the neuronal and inducible nitric-oxide synthase isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Structure-function aspects in the nitric oxide synthases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Drug concentration heterogeneity facilitates the evolution of drug resistance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

NO synthase isozymes have distinct substrate binding sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21276

21 January 2018

Identifiers

10.1074/JBC.274.30.21276

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