(Q27619756)

English

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

scientific article

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10500114%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes (English)

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31 October 2019

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31 October 2019

author name string

D A Matthews

1

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31 October 2019

P S Dragovich

2

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31 October 2019

S E Webber

3

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31 October 2019

S A Fuhrman

4

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31 October 2019

A K Patick

5

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31 October 2019

L S Zalman

6

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31 October 2019

T F Hendrickson

7

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31 October 2019

R A Love

8

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31 October 2019

T J Prins

9

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31 October 2019

J T Marakovits

10

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31 October 2019

R Zhou

11

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31 October 2019

J Tikhe

12

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31 October 2019

C E Ford

13

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31 October 2019

R A Ferre

15

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31 October 2019

E L Brown

16

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31 October 2019

S L Binford

17

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31 October 2019

M A Brothers

18

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31 October 2019

D M DeLisle

19

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31 October 2019

S T Worland

20

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31 October 2019

language of work or name

0 references

publication date

1 September 1999

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31 October 2019

number of pages

8

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inferred from page(s)

Proceedings of the National Academy of Sciences of the United States of America

1 reference

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31 October 2019

96

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31 October 2019

11000-11007

1 reference

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31 October 2019

20

1 reference

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31 October 2019

Refined X-ray crystallographic structure of the poliovirus 3C gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

20 March 2017

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

20 March 2017

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

20 March 2017

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Processing of a cellular polypeptide by 3CD proteinase is required for poliovirus ribonucleoprotein complex formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Poliovirus RNA synthesis utilizes an RNP complex formed around the 5'-end of viral RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Human rhinovirus-14 protease 3C (3Cpro) binds specifically to the 5'-noncoding region of the viral RNA. Evidence that 3Cpro has different domains for the RNA binding and proteolytic activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Weakly polar interactions in proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Viral proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Chemotherapy of rhinovirus colds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Viral proteinases: weakness in strength

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

29 September 2017

Picornavirus protein processing--enzymes, substrates, and genetic regulation

1 reference

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29 September 2017

Thrombin inhibitor design.

1 reference

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2 June 2018

Peptide aldehyde inhibitors of hepatitis A virus 3C proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

2 June 2018

Vinylogous amino acid esters: a new class of inactivators for thiol proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

2 June 2018

The major and minor group receptor families contain all but one human rhinovirus serotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34232

2 June 2018

Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships for inhibition of papain by peptide Michael acceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A consensus sequence for substrate hydrolysis by rhinovirus 3C proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.96.20.11000

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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31 October 2019

1999PNAS...9611000M

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10500114%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10500114%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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