(Q27622083)

English

An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism

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An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism (English)

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crystal structure

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author name string

T Shimizu

1

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K Ihara

2

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R Maesaki

3

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S Kuroda

4

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K Kaibuchi

5

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T Hakoshima

6

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language of work or name

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publication date

16 June 2000

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Journal of Biological Chemistry

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275

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24

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18311-7

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Rho GTPases and signaling networks

1 reference

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The structural basis of the activation of Ras by Sos

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Kinetics of interaction of Rab5 and Rab7 with nucleotides and magnesium ions

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Influence of Mg2+ on the structure and function of Rab5.

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Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: Two different nucleotide states in one crystal

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Crystal structure of RhoA-GDP and its functional implications

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Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

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Solvent content of protein crystals

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AMoRe: an automated package for molecular replacement

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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PROCHECK: a program to check the stereochemical quality of protein structures

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Raster3D Version 2.0. A program for photorealistic molecular graphics

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy.

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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

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The Dbl family of oncogenes

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Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

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NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

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Structure and mutagenesis of the Dbl homology domain

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GEF-mediated GDP/GTP exchange by monomeric GTPases: a regulatory role for Mg2+?

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GEFs: structural basis for their activation of small GTP-binding proteins

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Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP

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Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

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G protein mechanisms: insights from structural analysis

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Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

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The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

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Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein

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Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis

1 reference

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The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange

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Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP

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Structure of the conserved GTPase domain of the signal recognition particle

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Structural Basis for Activation of ARF GTPase

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Is there a rate-limiting step before GTP cleavage by H-ras p21?

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Identifiers

10.1074/JBC.M910274199

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release_mwzhxxw3r5edniqbtvtmpfeiku

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https://api.fatcat.wiki/v0/release/mwzhxxw3r5edniqbtvtmpfeiku

24 November 2022

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