(Q27630877)

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The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

crystal structure

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Hans Brandstetter

1

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6 November 2019

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Grams F

2

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6 November 2019

Glitz D

3

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6 November 2019

Lang A

4

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6 November 2019

Huber R

5

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6 November 2019

Bode W

6

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6 November 2019

Krell HW

7

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6 November 2019

Engh RA

8

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6 November 2019

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22 January 2001

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6 November 2019

Journal of Biological Chemistry

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6 November 2019

276

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6 November 2019

20

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6 November 2019

17405-17412

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6 November 2019

Matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Relating matrix metalloproteinase structure to function: why the "hemopexin" domain?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

ECM and cell surface proteolysis: regulating cellular ecology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structural properties of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structure of human neutrophil collagenase reveals large S1' specificity pocket

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Direct activation of human neutrophil procollagenase by recombinant stromelysin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Biochemical characterization of human collagenase-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Design and synthesis of heterotrimeric collagen peptides with a built-in cystine-knot. Models for collagen catabolism by matrix-metalloproteases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Crystal structure of the stromelysin catalytic domain at 2.0 A resolution: inhibitor-induced conformational changes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Crystal structures of matrilysin-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Bis-substituted malonic acid hydroxamate derivatives as inhibitors of human neutrophil collagenase (MMP8).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

The detection of sub-units within the crystallographic asymmetric unit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

AMoRe: an automated package for molecular replacement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Accurate bond and angle parameters for X-ray protein structure refinement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

C-H...O hydrogen bonding in biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP Methods

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Identification and characterization of a novel collagenase in Xenopus laevis: possible roles during frog development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Structure of recombinant mouse collagenase-3 (MMP-13)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Hydrolysis of triple-helical collagen peptide models by matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007475200

21 January 2018

Identifiers

10.1074/JBC.M007475200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278347%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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