(Q27634614)

English

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents

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Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents (English)

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author name string

M A Seefeld

1

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W H Miller

2

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K A Newlander

3

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W J Burgess

4

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D J Payne

5

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S F Rittenhouse

6

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T D Moore

7

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W E DeWolf

8

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P M Keller

9

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X Qiu

10

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C A Janson

11

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K Vaidya

12

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A P Fosberry

13

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M G Smyth

14

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D D Jaworski

15

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C Slater-Radosti

16

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W F Huffman

17

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publication date

3 September 2001

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Bioorganic & Medicinal Chemistry Letters

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11

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17

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2241-4

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The crisis in antibiotic resistance

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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New directions in antibacterial research

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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Fatty acid metabolism in bacteria

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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The enoyl-[acyl-carrier-protein] reductase (FabI) of Escherichia coli, which catalyzes a key regulatory step in fatty acid biosynthesis, accepts NADH and NADPH as cofactors and is inhibited by palmitoyl-CoA.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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Enoyl-Acyl Carrier Protein Reductase (fabI) Plays a Determinant Role in Completing Cycles of Fatty Acid Elongation in Escherichia coli

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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Molecular basis of triclosan activity

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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Molecular basis for triclosan activity involves a flipping loop in the active site

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https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

based on heuristic

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Mechanism of triclosan inhibition of bacterial fatty acid synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

based on heuristic

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Plasmids and bacterial resistance to biocides

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2801%2900405-X

7 January 2021

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Identifiers

10.1016/S0960-894X(01)00405-X

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