(Q27637344)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

enoyl-acyl carrier reductase

6 December 2019

main subject

1 reference

GeneDB

10 September 2018

1 reference

24 September 2018

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author

William Jacobs

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

David A. Fidock

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

author name string

Remo Perozzo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Mack Kuo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Amar bir Singh Sidhu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Jacob T Valiyaveettil

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Robert Bittman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

James C Sacchettini

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

language of work or name

English

0 references

publication date

15 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

volume

277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

page(s)

13106-13114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum

6 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A plastid of probable green algal origin in Apicomplexan parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A plastid organelle as a drug target in apicomplexan parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Effects of interruption of apicoplast function on malaria infection, development, and transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A plastid segregation defect in the protozoan parasite Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Second-hand chloroplasts and the case of the disappearing nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Plastids in parasites of humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Apicomplexan plastids as drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Origin, targeting, and function of the apicomplexan plastid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Escherichia coli as a model for the regulation of dissociable (type II) fatty acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Fatty acid metabolism in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

The use of a hybrid genetic system to study the functional relationship between prokaryotic and plant multi-enzyme fatty acid synthetase complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Triclosan targets lipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Control and eradication of methicillin-resistant Staphylococcus aureus on a surgical unit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Handwashing in a neonatal intensive care nursery: product acceptability and effectiveness of chlorhexidine gluconate 4% and triclosan 1%

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

AMoRe: an automated package for molecular replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A Second-Generation Catalyst for Aryl Halide Amination: Mixed Secondary Amines from Aryl Halides and Primary Amines Catalyzed by (DPPF)PdCl2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A Plasmodium falciparum protein kinase with two unusually large kinase inserts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Molecular cloning and characterization of a putative glutathione reductase gene, the PfGR2 gene, from Plasmodium falciparum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Deletion of the parasite-specific insertions and mutation of the catalytic triad in glutathione reductase from chloroquine-sensitive Plasmodium falciparum 3D7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Prediction of N-terminal protein sorting signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Chemical and biological evolution of nucleotide-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Crystallographic analysis of triclosan bound to enoyl reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Molecular basis for triclosan activity involves a flipping loop in the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

A mechanism of drug action revealed by structural studies of enoyl reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Common themes in redox chemistry emerge from the X-ray structure of oilseed rape (Brassica napus) enoyl acyl carrier protein reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Structural basis and mechanism of enoyl reductase inhibition by triclosan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Inhibitor binding studies on enoyl reductase reveal conformational changes related to substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Purification and characterizations of beta-Ketoacyl-[acyl-carrier-protein] reductase, beta-hydroxyacyl-[acyl-carrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia oleracea leaves

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Plastid in human parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Triclosan: applications and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

The X-ray structure of Escherichia coli enoyl reductase with bound NAD+ at 2.1 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase fromMycobacterium tuberculosis†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112000200

21 January 2018

Identifiers

DOI

10.1074/JBC.M112000200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11792710%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference