(Q27638205)

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Structural determinants of the Na+/H+ exchanger regulatory factor interaction with the beta 2 adrenergic and platelet-derived growth factor receptors

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scholarly article

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Structural determinants of the Na+/H+ exchanger regulatory factor interaction with the beta 2 adrenergic and platelet-derived growth factor receptors (English)

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author name string

Subramanian Karthikeyan

1

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Teli Leung

2

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John A A Ladias

3

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language of work or name

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publication date

24 May 2002

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Journal of Biological Chemistry

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277

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21

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18973-8

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Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger

1 reference

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Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

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NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins

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A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins

1 reference

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The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

1 reference

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Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity

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The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane

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Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction

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A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

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PDZ domains: structural modules for protein complex assembly

1 reference

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Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

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Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

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Crystal structure of a PDZ domain

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Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels

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Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex

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Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains

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Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator

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Peptide-surface association: the case of PDZ and PTB domains

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Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

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MOLREP: an Automated Program for Molecular Replacement

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

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Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA

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NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas

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Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

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Raster3D Version 2.0. A program for photorealistic molecular graphics

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

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Identifiers

10.1074/JBC.M201507200

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