(Q27639479)

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Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export

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Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export (English)

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protein structure

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author name string

Wuyi Meng

1

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Lora L Swenson

2

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Matthew J Fitzgibbon

3

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Koto Hayakawa

4

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Ernst Ter Haar

5

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Anne E Behrens

6

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John R Fulghum

7

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Judith A Lippke

8

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language of work or name

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publication date

4 October 2002

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Journal of Biological Chemistry

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277

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40

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37401-5

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Mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

The p38 signal transduction pathway: activation and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

LSP1 is the major substrate for mitogen-activated protein kinase-activated protein kinase 2 in human neutrophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

The primary structure of a human MAP kinase activated protein kinase 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Characterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Integration of macromolecular diffraction data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Automated protein model building combined with iterative structure refinement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Characterization of an autoinhibitory domain in human mitogen-activated protein kinase-activated protein kinase 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Insights into autoregulation from the crystal structure of twitchin kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200418200

21 January 2018

Identifiers

10.1074/JBC.C200418200

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release_m6drjcms3bfpldoryrkarpwuwm

1 reference

https://api.fatcat.wiki/v0/release/m6drjcms3bfpldoryrkarpwuwm

24 November 2022

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