(Q27639514)

English

Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)

scientific article

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Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151) (English)
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Simon J F Macdonald
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Michael D Dowle
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Lee A Harrison
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Geoffrey D E Clarke
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Graham G A Inglis
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Martin R Johnson
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Pritom Shah
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Robin A Smith
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Augustin Amour
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Gill Fleetwood
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Davina C Humphreys
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Christopher R Molloy
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Mary Dixon
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Rosalind E Godward
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Alan J Wonacott
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Onkar M P Singh
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Simon T Hodgson
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George W Hardy
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29 August 2002
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45
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18
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3878-90
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