(Q27640083)

6 July 2017

title

Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain (English)

1 reference

6 July 2017

0 references

J N Varghese

1

J N

Varghese

1 reference

6 July 2017

R L Moritz

2

R L

Moritz

1 reference

6 July 2017

M-Z Lou

3

M-Z

Lou

1 reference

6 July 2017

A Van Donkelaar

4

A

Van Donkelaar

1 reference

6 July 2017

H Ji

5

H

Ji

1 reference

6 July 2017

N Ivancic

6

N

Ivancic

1 reference

6 July 2017

K M Branson

7

K M

Branson

1 reference

6 July 2017

N E Hall

8

N E

Hall

1 reference

6 July 2017

R J Simpson

9

R J

Simpson

1 reference

6 July 2017

language of work or name

English

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publication date

2 December 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 July 2017

published in

1 reference

6 July 2017

volume

99

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6 July 2017

issue

25

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6 July 2017

page(s)

15959-15964

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Structure of an extracellular gp130 cytokine receptor signaling complex

6 July 2017

cites work

1 reference

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Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Solution structure of recombinant human interleukin-6

20 March 2017

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Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130

20 March 2017

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Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

20 March 2017

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

20 March 2017

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Structure of a Fibronectin Type III Domain from Tenascin Phased by MAD Analysis of the Selenomethionyl Protein

20 March 2017

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20 March 2017

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Automated MAD and MIR structure solution

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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Shape complementarity at protein/protein interfaces

20 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

20 March 2017

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Modelling protein docking using shape complementarity, electrostatics and biochemical information

20 March 2017

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Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism

20 March 2017

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The immunoglobulin fold. Structural classification, sequence patterns and common core

20 March 2017

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Interleukin-6 family of cytokines and gp130

20 March 2017

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Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

20 March 2017

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Structural design and molecular evolution of a cytokine receptor superfamily

20 March 2017

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7 April 2017

https://api.crossref.org/works/10.1073%2FPNAS.232432399

The paradigm of IL-6: from basic science to medicine

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

The soluble interleukin 6 receptor: mechanisms of production and implications in disease

29 September 2017

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Anti-interleukin 6 receptor antibody treatment in rheumatic disease

29 September 2017

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Receptor recognition by gp130 cytokines

29 September 2017

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IL-6 type cytokine receptor complexes: hexamer, tetramer or both?

29 September 2017

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The membrane proximal cytokine receptor domain of the human interleukin-6 receptor is sufficient for ligand binding but not for gp130 association

29 September 2017

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Rapid refinement of protein interfaces incorporating solvation: application to the docking problem

29 September 2017

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Interleukin-6: structure-function relationships.

29 September 2017

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Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor.

29 September 2017

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Soluble cytokine receptors

29 September 2017

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29 September 2017

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Interleukin-6 receptor and a unique mechanism of its signal transduction

29 September 2017

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The soluble interleukin-6 receptor is generated by shedding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Use of a biosensor with surface plasmon resonance detection for the determination of binding constants: measurement of interleukin-6 binding to the soluble interleukin-6 receptor.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Interleukin-6: a candidate mediator of human prostate cancer morbidity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor alpha mutated in the predicted gp130-binding interface

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Epitope analysis of human IL-6 receptor gp80 molecule with monoclonal antibodies

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Purification and characterization of soluble human IL-6 receptor expressed in CHO cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Involvement of interleukin-6 and prostaglandin E2 in periarticular osteoporosis of postmenopausal women with rheumatoid arthritis

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

Protein Crystal Diffraction Patterns Using a Capillary-Focused Synchrotron X-ray Beam

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

Disulfide Bond Structure andN-Glycosylation Sites of the Extracellular Domain of the Human Interleukin-6 Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

Determination of the Disulfide Structure andN-Glycosylation Sites of the Extracellular Domain of the Human Signal Transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

Use of pair potentials across protein interfaces in screening predicted docked complexes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138547

Electrostatic complementarity at protein/protein interfaces

27 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6 (IL-6)-Binding Sites of the Human IL-6 Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232432399

High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130

21 January 2018

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12 December 2020

Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies

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12 December 2020

Analysis of the human interleukin-6/human interleukin-6 receptor binding interface at the amino acid level: proposed mechanism of interaction

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12 December 2020

The Immunoglobulin Fold

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12 December 2020

Identifiers

DOI

10.1073/PNAS.232432399

1 reference

6 July 2017

0 references

1 reference

6 July 2017

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