(Q27641126)

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The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis

scientific article (publication date: 9 May 2003)

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Europe PubMed Central

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3 November 2019

The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis (English)

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3 November 2019

amyotrophic lateral sclerosis

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Svetlana Antonyuk

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3 November 2019

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3 November 2019

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Richard W Strange

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3 November 2019

Peter A Doucette

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3 November 2019

Jorge A Rodriguez

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3 November 2019

P John Hart

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3 November 2019

Lawrence J Hayward

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3 November 2019

Joan S Valentine

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3 November 2019

S Samar Hasnain

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3 November 2019

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1 May 2003

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3 November 2019

Journal of Molecular Biology

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3 November 2019

328

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3 November 2019

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3 November 2019

877-891

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3 November 2019

Superoxide dismutases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase

1 reference

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7 January 2021

Electrostatic recognition between superoxide and copper, zinc superoxide dismutase

1 reference

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7 January 2021

An extended-X-ray-absorption-fine-structure study of bovine erythrocyte superoxide dismutase in aqueous solution. Direct evidence for three-co-ordinate Cu(I) in reduced enzyme

1 reference

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7 January 2021

Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase

1 reference

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7 January 2021

A critical assessment of the evidence from XAFS and crystallography for the breakage of the imidazolate bridge during catalysis in CuZn superoxide dismutase

1 reference

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7 January 2021

Evidence of his61 imidazolate bridge rupture in reduced crystalline Cu,Zn superoxide dismutase.

1 reference

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7 January 2021

Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis

1 reference

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7 January 2021

Crystallographic structures of bovine copper-zinc superoxide dismutase reveal asymmetry in two subunits: functionally important three and five coordinate copper sites captured in the same crystal

1 reference

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7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Characterization of three yeast copper-zinc superoxide dismutase mutants analogous to those coded for in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

The metal binding properties of the zinc site of yeast copper-zinc superoxide dismutase: implications for amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Superoxide dismutase and the death of motoneurons in ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900355-3

7 January 2021

Amyotrophic lateral sclerosis: a proposed mechanism

1 reference

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7 January 2021

Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase

1 reference

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7 January 2021

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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7 January 2021

Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase

1 reference

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7 January 2021

Stereochemical quality of protein structure coordinates

1 reference

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7 January 2021

A structure-based mechanism for copper-zinc superoxide dismutase

1 reference

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7 January 2021

Direct detection of hydrogen bonds in monomeric superoxide dismutase: biological implications

1 reference

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7 January 2021

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

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7 January 2021

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

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7 January 2021

Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state

1 reference

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7 January 2021

MOLREP: an Automated Program for Molecular Replacement

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7 January 2021

A graphics model building and refinement system for macromolecules

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7 January 2021

Automated refinement of protein models

1 reference

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7 January 2021

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

1 reference

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7 January 2021

AMoRe: an automated package for molecular replacement

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7 January 2021

Identifiers

10.1016/S0022-2836(03)00355-3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729761%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729761%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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