(Q27641908)

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Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941311%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941311%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Rebecca Ellston

3

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7 November 2019

author name string

John F Beattie

1

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7 November 2019

Gloria A Breault

2

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7 November 2019

Stephen Green

4

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7 November 2019

Philip J Jewsbury

5

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7 November 2019

Catherine J Midgley

6

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7 November 2019

Russell T Naven

7

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7 November 2019

Claire A Minshull

8

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7 November 2019

Richard A Pauptit

9

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7 November 2019

Julie A Tucker

10

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7 November 2019

J Elizabeth Pease

11

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7 November 2019

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publication date

1 September 2003

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7 November 2019

number of pages

6

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Bioorganic & Medicinal Chemistry Letters

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7 November 2019

13

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7 November 2019

18

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7 November 2019

2955-2960

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941311%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Cancer cell cycles

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin D1 in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The INK4 family of cell cycle inhibitors in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The Rb/E2F pathway and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of selective inhibitors of cyclin dependent kinase 4

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-based generation of a new class of potent Cdk4 inhibitors: new de novo design strategy and library design

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel approach for the development of selective Cdk4 inhibitors: library design based on locations of Cdk4 specific amino acid residues

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

5-Arylamino-2-methyl-4,7-dioxobenzothiazoles as inhibitors of cyclin-dependent kinase 4 and cytotoxic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900202-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0960-894X(03)00202-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941311%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941311%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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