(Q27641969)

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Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates

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scholarly article

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Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates (English)

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Drosophila melanogaster

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author name string

Shin Numao

1

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Douglas A Kuntz

2

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Stephen G Withers

3

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David R Rose

4

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language of work or name

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publication date

28 November 2003

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Journal of Biological Chemistry

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278

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48

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48074-83

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The dolichol pathway of N-linked glycosylation

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Importance of glycosidases in mammalian glycoprotein biosynthesis

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Assembly of asparagine-linked oligosaccharides

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Metastases: the glycan connection

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Glycoprotein glycosylation and cancer progression

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Suppression of tumor growth and metastasis in Mgat5-deficient mice

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A classification of glycosyl hydrolases based on amino acid sequence similarities

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New families in the classification of glycosyl hydrolases based on amino acid sequence similarities

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Catalytic mechanism of enzymic glycosyl transfer

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Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells

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Mapping the conformational itinerary of beta-glycosidases by X-ray crystallography

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Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase

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Substrate distortion by a beta-mannanase: snapshots of the Michaelis and covalent-intermediate complexes suggest a B(2,5) conformation for the transition state

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X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family

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Processing of X-ray diffraction data collected in oscillation mode

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Molecular dynamics applied to X-ray structure refinement

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Improved methods for building protein models in electron density maps and the location of errors in these models

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The Protein Data Bank

1 reference

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Unequivocal identification of Asp-214 as the catalytic nucleophile of Saccharomyces cerevisiae alpha-glucosidase using 5-fluoro glycosyl fluorides

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Glycosidase mechanisms

1 reference

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Glycosidase families

1 reference

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Human lysosomal and jack bean alpha-mannosidases are retaining glycosidases

1 reference

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Glycosidase mechanisms: anatomy of a finely tuned catalyst

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Identification of the active site nucleophile in jack bean alpha-mannosidase using 5-fluoro-beta-L-gulosyl fluoride

1 reference

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Identification of Asp197 as the catalytic nucleophile in the family 38 alpha-mannosidase from bovine kidney lysosomes

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M309249200

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