(Q27648699)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

0 references

0 references

Helicobacter pylori infectious disease

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Timothy L. Cover

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Kelly A Gangwer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Darren J Mushrush

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Devin L Stauff

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Ben Spiller

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

D Borden Lacy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

2 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

8 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

16293-16298

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

Structure of Bordetella pertussis virulence factor P.69 pertactin

8 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

20 March 2017

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

ESPript: analysis of multiple sequence alignments in PostScript

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

20 March 2017

https://api.crossref.org/works/10.1073/PNAS.0707447104

Improved methods for building protein models in electron density maps and the location of errors in these models

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Situs: A package for docking crystal structures into low-resolution maps from electron microscopy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Paired cysteine residues are required for high levels of the Helicobacter pylori autotransporter VacA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Pertactin beta-helix folding mechanism suggests common themes for the secretion and folding of autotransporter proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

The cell-specific phenotype of the polymorphic vacA midregion is independent of the appearance of the cell surface receptor protein tyrosine phosphatase beta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Helicobacter pylori VacA, a paradigm for toxin multifunctionality

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Membrane channel structure of Helicobacter pylori vacuolating toxin: role of multiple GXXXG motifs in cylindrical channels.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

The quest for a vaccine against Helicobacter pylori: how to move from mouse to man?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Outer membrane targeting of passenger proteins by the vacuolating cytotoxin autotransporter of Helicobacter pylori

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Two distinctive cell binding patterns by vacuolating toxin fused with glutathione S-transferase: one high-affinity m1-specific binding and the other lower-affinity binding for variant m forms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Expression and binding analysis of GST-VacA fusions reveals that the C-terminal approximately 100-residue segment of exotoxin is crucial for binding in HeLa cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Cell specificity of Helicobacter pylori cytotoxin is determined by a short region in the polymorphic midregion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase beta.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

VacA from Helicobacter pylori: a hexameric chloride channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Free recombination within Helicobacter pylori

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Three-dimensional reconstruction of metal replicas of the Helicobacter pylori vacuolating cytotoxin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Binding and internalization of the Helicobacter pylori vacuolating cytotoxin by epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Purification and characterization of the vacuolating toxin from Helicobacter pylori

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2042200

Helicobacter pyloriInfection

19 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

The concerted action of the Helicobacter pylori cytotoxin VacA and of the v-ATPase proton pump induces swelling of isolated endosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Interactions between p-33 and p-55 Domains of theHelicobacter pyloriVacuolating Cytotoxin (VacA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Crystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Fold recognition and accurate sequence-structure alignment of sequences directing beta-sheet proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Development of a mouse model of Helicobacter pylori infection that mimics human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Genetic variability determinants of Helicobacter pylori: influence of clinical background and geographic origin of isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0707447104

Identification of the minimal intracellular vacuolating domain of the Helicobacter pylori vacuolating toxin

21 January 2018

1 reference

12 December 2020

A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation

1 reference

12 December 2020

Functional complementation reveals the importance of intermolecular monomer interactions for Helicobacter pylori VacA vacuolating activity

1 reference

12 December 2020

A conserved region within the Bordetella pertussis autotransporter BrkA is necessary for folding of its passenger domain

1 reference

12 December 2020

Human gastric glycosphingolipids recognized by Helicobacter pylori vacuolating cytotoxin VacA

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0707447104

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

ADS bibcode

2007PNAS..10416293G

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911250%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references