(Q27649001)

English

Crystal Structure of the Retinoblastoma Protein N Domain Provides Insight into Tumor Suppression, Ligand Interaction, and Holoprotein Architecture

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scholarly article

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Europe PubMed Central

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10 January 2020

Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996702%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

0 references

crystal structure

0 references

protein structure

0 references

1 reference

based on heuristic

inferred from title

1

1 reference

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10 January 2020

8

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10 January 2020

author name string

Shradha Singh

2

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10 January 2020

Wyatt W Yue

3

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10 January 2020

Maciej Luczynski

4

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10 January 2020

Rachid Lakbir

5

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10 January 2020

Francisco Sanchez-Sanchez

6

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10 January 2020

Thomas Bader

7

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10 January 2020

Sibylle Mittnacht

9

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10 January 2020

publication date

1 November 2007

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10 January 2020

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10 January 2020

28

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10 January 2020

3

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10 January 2020

371-385

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10 January 2020

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors

1 reference

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20 March 2017

Selective ablation of retinoblastoma protein function by the RET finger protein

1 reference

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20 March 2017

Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation

1 reference

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20 March 2017

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

1 reference

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20 March 2017

Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

1 reference

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20 March 2017

A novel Rb- and p300-binding protein inhibits transactivation by MyoD

1 reference

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20 March 2017

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

1 reference

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20 March 2017

Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

1 reference

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20 March 2017

Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

The crystal structure of human cyclin H

1 reference

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20 March 2017

The crystal structure of cyclin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Binding of an interferon-inducible protein (p202) to the retinoblastoma protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Crystal structure of a TFIIB-TBP-TATA-element ternary complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

The integration of macromolecular diffraction data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Rb interacts with TAF(II)250/TFIID through multiple domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

20 March 2017

Unraveling hot spots in binding interfaces: progress and challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

7 April 2017

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

7 April 2017

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

The retinoblastoma protein--from bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Rb enhances p160/SRC coactivator-dependent activity of nuclear receptors and hormone responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

How the other half lives, the amino‐terminal domain of the retinoblastoma tumor suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

The retinoblastoma tumour suppressor in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Tumor suppression by a severely truncated species of retinoblastoma protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Role of the LXCXE binding site in Rb function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Evaluation of macromolecular electron-density map quality using the correlation of local r.m.s. density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Constitutional RB1-gene mutations in patients with isolated unilateral retinoblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Molecular etiology of low-penetrance retinoblastoma in two pedigrees.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

29 September 2017

A constitutional homozygous mutation in the RB1 gene in a patient with unilateral retinoblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

2 June 2018

The cyclin box fold: protein recognition in cell-cycle and transcription control

1 reference

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2 June 2018

Attenuation of disease phenotype through alternative translation initiation in low-penetrance retinoblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

27 November 2018

Unilateral retinoblastoma, lack of familial history and older age does not exclude germline RB1 gene mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

27 November 2018

A T to C mutation in the polypyrimidine tract of the exon 9 splicing site of the RB1 gene responsible for low penetrance hereditary retinoblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

27 November 2018

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

27 November 2018

Spectrum of germline mutations in the RB1 gene: a study of 232 patients with hereditary and non hereditary retinoblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4944837

27 November 2018

Retinoblastoma susceptibility protein, Rb, possesses multiple BRCT-Ws, BRCA1 carboxyl-terminus-related W regions with DNA break-binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17996702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 contains a DNA break-binding motif similar to the functional part of BRCT-related region of Rb

1 reference

https://pubmed.ncbi.nlm.nih.gov/17996702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germline mutations in the RB1 gene in patients with hereditary retinoblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17996702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel RB1 gene constitutional mutations found in Polish patients with familial and/or bilateral retinoblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17996702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17996702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of germline mutations in the RB1 gene by denaturant gradient gel electrophoresis and polymerase chain reaction direct sequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17996702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLCEL.2007.08.023

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996702%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996702%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996702%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

ResearchGate publication ID

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