(Q27649121)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Structures of prostacyclin synthase and its complexes with substrate analog and inhibitor reveal a ligand-specific heme conformation change (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

Prostaglandin I2 synthase

27 December 2019

main subject

cell biology

0 references

1 reference

GOA release 2020-03-11

heme binding

1 reference

Prostaglandin I2 (prostacyclin) synthase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Nei-Li Chan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Yi-Ching Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Chia-Wang Chiang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Hui-Chun Yeh

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Pei-Yung Hsu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Frank G Whitby

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Lee-Ho Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

English

0 references

publication date

21 November 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

27 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

283

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

2917-2926

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

Crystal structure of the human prostacyclin synthase

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Likelihood-enhanced fast translation functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Automated main-chain model building by template matching and iterative fragment extension

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Maximum-likelihood density modification

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Spectral evidence for the cytochrome P450 nature of prostacyclin synthetase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

On the mechanism of prostacyclin and thromboxane A2 biosynthesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Reaction mechanisms of 15-hydroperoxyeicosatetraenoic acid catalyzed by human prostacyclin and thromboxane synthases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

What common structural features and variations of mammalian P450s are known to date?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Mechanisms of reaction in cytochrome P450: Hydroxylation of camphor in P450cam.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Structure-function analysis of cytochromes P450 2B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

The ins and outs of cytochrome P450s.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

The role of the heme propionates in heme biochemistry.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Characterization of heme environment and mechanism of peroxide bond cleavage in human prostacyclin synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Do mammalian cytochrome P450s show multiple ligand access pathways and ligand channelling?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Cytochrome P450: nature's most versatile biological catalyst

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Crystallization of cytochromes P450 and substrate-enzyme interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Automated side-chain model building and sequence assignment by template matching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Exceptionally stable salt bridges in cytochrome P450cam have functional roles.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Molecular cloning and characterization of bovine prostacyclin synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Chemical stability of prostacyclin (PGI2) in aqueous solutions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

The effect of heme environment on the hydrogen abstraction reaction of camphor in P450cam catalysis: a QM/MM study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2293295

Structure and function of cytochromes P450: a comparative analysis of three crystal structures.

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707470200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707470200

Use of low-molecular-weight polyethylene glycol in the crystallization of RNA oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707470200

Prostacyclin and Thromboxane Synthase: New Aspects of Hemethiolate Catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707470200

What is the Active Species of Cytochrome P450 during Camphor Hydroxylation? QM/MM Studies of Different Electronic States of Compound I and of Reduced and Oxidized Iron−Oxo Intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707470200

Electrochemistry and Spectroelectrochemistry of .sigma.-Bonded Iron(III) Porphyrins with Nonplanar Porphyrin Rings. Reactions of (OETPP)Fe(R) and (OETPP)FeCl, Where R = C6H5, C6F4H, or C6F5 and OETPP Is the Dianion of 2,3,7,8,12,13,17,18-Octaethyl-5,

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707470200

Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines

21 January 2018

1 reference

12 December 2020

Studies on the interaction of minoxidil with prostacyclin synthase in vitro

1 reference

12 December 2020

Radioimmunological assay of prostacyclin synthetase activity

1 reference

12 December 2020

Glu318 and Thr319 mutations of cytochrome P450 1A2 remarkably enhance homolytic O-O cleavage of alkyl hydroperoxides. An optical absorption spectral study

1 reference

12 December 2020

Essential role of the Arg112 residue of cytochrome P450cam for electron transfer from reduced putidaredoxin

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M707470200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18032380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

18032380

1 reference