(Q27650294)

English

2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis

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2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis (English)

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phosphorylation

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based on heuristic

inferred from title

author name string

Yuko Tone

1

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Lars C Pedersen

2

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Tomoko Yamamoto

3

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Tomomi Izumikawa

4

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Hiroshi Kitagawa

5

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Junko Nishihara

6

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Jun-Ichi Tamura

7

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Masahiko Negishi

8

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Kazuyuki Sugahara

9

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language of work or name

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publication date

13 June 2008

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Journal of Biological Chemistry

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283

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24

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16801-7

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In vitro polymerization of heparan sulfate backbone by the EXT proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423269

20 March 2017

Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis

1 reference

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20 March 2017

Molecular cloning and expression of a human chondroitin synthase

1 reference

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20 March 2017

Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis

1 reference

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20 March 2017

The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

1 reference

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20 March 2017

Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I

1 reference

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20 March 2017

Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues

1 reference

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20 March 2017

1 reference

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20 March 2017

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1 reference

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20 March 2017

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2 references

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20 March 2017

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1 reference

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1 reference

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20 March 2017

Characterization of recombinant human glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans

1 reference

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20 March 2017

Structural basis for acceptor substrate recognition of a human glucuronyltransferase, GlcAT-P, an enzyme critical in the biosynthesis of the carbohydrate epitope HNK-1

1 reference

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20 March 2017

Specificities of heparan sulphate proteoglycans in developmental processes

1 reference

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20 March 2017

The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate

1 reference

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20 March 2017

Core protein structure and sequence determine the site and presence of heparan sulfate and chondroitin sulfate on syndecan-1

1 reference

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20 March 2017

Heparin-binding growth factor, pleiotrophin, mediates neuritogenic activity of embryonic pig brain-derived chondroitin sulfate/dermatan sulfate hybrid chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423269

20 March 2017

Molecular cloning and expression of glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423269

20 March 2017

pEF-BOS, a powerful mammalian expression vector

1 reference

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7 April 2017

Chondroitin/dermatan sulfate in the central nervous system

1 reference

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29 September 2017

Demonstration of the pleiotrophin-binding oligosaccharide sequences isolated from chondroitin sulfate/dermatan sulfate hybrid chains of embryonic pig brains

1 reference

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29 September 2017

Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-pro

1 reference

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29 September 2017

Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate

1 reference

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29 September 2017

Molecular Cloning of a Chondroitin Polymerizing Factor That Cooperates with Chondroitin Synthase for Chondroitin Polymerization

1 reference

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29 September 2017

Chondroitin sulphate proteoglycans in the CNS injury response

1 reference

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29 September 2017

Structural characterization of heparan sulfate and chondroitin sulfate of syndecan-1 purified from normal murine mammary gland epithelial cells. Common phosphorylation of xylose and differential sulfation of galactose in the protein linkage region t

1 reference

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29 September 2017

Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans

1 reference

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29 September 2017

The elusive functions of proteoglycans: in vivo veritas

1 reference

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29 September 2017

Molecular interactions of neural chondroitin sulfate proteoglycans in the brain development

1 reference

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29 September 2017

Initiation of galactosaminoglycan biosynthesis. Separate galactosylation and dephosphorylation pathways for phosphoxylosylated decorin protein and exogenous xyloside

1 reference

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1 reference

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29 September 2017

Heparan sulfate: a piece of information

1 reference

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29 September 2017

Proteoglycans in the nervous system

1 reference

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29 September 2017

Proteoglycans in health and disease: structures and functions

1 reference

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29 September 2017

Involvement of chondroitin sulfate synthase-3 (chondroitin synthase-2) in chondroitin polymerization through its interaction with chondroitin synthase-1 or chondroitin-polymerizing factor

1 reference

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2 June 2018

Increased incidence of unsulphated and 4-sulphated residues in the chondroitin sulphate linkage region observed by high-pH anion-exchange chromatography

1 reference

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2 June 2018

Structural studies on sulfated glycopeptides from the carbohydrate-protein linkage region of chondroitin 4-sulfate proteoglycans of swarm rat chondrosarcoma. Demonstration of the structure Gal(4-O-sulfate)beta 1-3Gal beta 1-4XYL beta 1-O-Ser.

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2 June 2018

Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin 6-sulfate proteoglycans of shark cartilage. I. Six compounds containing 0 or 1 sulfate and/or phosphate residues

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2 June 2018

Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors. Implications as a physiological binding partner in the brain and other tissues

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Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control bindin

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21 January 2018

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21 January 2018

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1 reference

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21 January 2018

Synthesis of phosphorylated and sulfated glycosyl serines in the linkage region of the glycosaminoglycans

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

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21 January 2018

Stereoselective syntheses of phosphorylated and sulfated glycosyl serines in glycosaminoglycan for biological probes

1 reference

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Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin 6-sulfate proteoglycans of shark cartilage. II. Seven compounds containing 2 or 3 sulfate residues

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1 reference

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1 reference

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10.1074/JBC.M709556200

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