(Q27653164)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

Malene Ringkjøbing Jensen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Flemming Hansen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Erika E Büllesbach

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Mathias A S Hass

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Søren M Kristensen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Christian Schwabe

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Jens J Led

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

1 December 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

13308-13317

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

Structure of human insulin monomer in water/acetonitrile solution

18 January 2020

cites work

1 reference

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PREDITOR: a web server for predicting protein torsion angle restraints

20 March 2017

1 reference

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The disulphide bonds of insulin

20 March 2017

1 reference

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Activation of orphan receptors by the hormone relaxin

20 March 2017

1 reference

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Flexibility and bioactivity of insulin: an NMR investigation of the solution structure and folding of an unusually flexible human insulin mutant with increased biological activity

20 March 2017

1 reference

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Solution structures of the R6 human insulin hexamer,

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta

20 March 2017

1 reference

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Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin

20 March 2017

1 reference

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Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The structure of 2Zn pig insulin crystals at 1.5 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Receptor binding redefined by a structural switch in a mutant human insulin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The Xplor-NIH NMR molecular structure determination package

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Identification of Relaxin-3/INSL7 as an Endogenous Ligand for the Orphan G-protein-coupled Receptor GPCR135

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Identification of Relaxin-3/INSL7 as a Ligand for GPCR142

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

ARIA2: automated NOE assignment and data integration in NMR structure calculation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Atomic Positions in Rhombohedral 2-Zinc Insulin Crystals

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Improved spectral resolution in cosy 1H NMR spectra of proteins via double quantum filtering

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The insulin receptor: a prototype for dimeric, allosteric membrane receptors?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Structural insights into ligand-induced activation of the insulin receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Cooperative binding of insulin-like Peptide 3 to a dimeric relaxin family peptide receptor 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Defining the LGR8 residues involved in binding insulin-like peptide 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Structure of the insulin receptor ectodomain reveals a folded-over conformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Insulin-like 3 signalling in testicular descent

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Identification of INSL5, a new member of the insulin superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Estimation of signal intensities in 2D NMR spectra with severe baseline distortion by combined linear-prediction and least-squares analyses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Structure and dynamics of des-pentapeptide-insulin in solution: the molten-globule hypothesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Site-site interactions among insulin receptors. Characterization of the negative cooperativity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

X-ray structure of human relaxin at 1.5 pComparison to insulin and implications for receptor binding determinants

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Relaxin: a disulfide homolog of insulin

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Synthetic cross-links arrest the C-terminal region of the relaxin-like factor in an active conformation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645033

Identification, chromosomal mapping, and partial characterization of mouse InsI6: a new member of the insulin family

27 November 2018

1 reference

12 December 2020

A comparison of the dynamic behavior of monomeric and dimeric insulin shows structural rearrangements in the active monomer

1 reference

12 December 2020

A transgenic insertion causing cryptorchidism in mice

1 reference

12 December 2020

Relaxin and its structural relationship to insulin

1 reference

12 December 2020

Comparative 2D NMR studies of human insulin and des-pentapeptide insulin: sequential resonance assignment and implications for protein dynamics and receptor recognition

1 reference

12 December 2020

Heteronuclear 2D NMR studies of an engineered insulin monomer: assignment and characterization of the receptor-binding surface by selective 2H and 13C labeling with application to protein design

1 reference

12 December 2020

Temperature dependence of 1H chemical shifts in proteins

1 reference

12 December 2020

Tryptophan B27 in the relaxin-like factor (RLF) is crucial for RLF receptor-binding

1 reference

12 December 2020

Chiral mutagenesis of insulin. Contribution of the B20-B23 beta-turn to activity and stability

1 reference

12 December 2020

The primary structure and the disulfide links of the bovine relaxin-like factor (RLF)

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI801412W

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19086273%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

19086273

1 reference