(Q27657767)

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Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

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scholarly article

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Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA (English)

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6

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author name string

Andrej Kolarovic

1

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Emma Schweizer

2

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Emily Greene

3

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Mark Gironda

4

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Pradeep S Pallan

5

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Eriks Rozners

7

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language of work or name

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publication date

21 October 2009

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Journal of the American Chemical Society

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131

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41

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14932-7

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Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

20 March 2017

A single 2'-hydroxyl group converts B-DNA to A-DNA. Crystal structure of the DNA-RNA chimeric decamer duplex d(CCGGC)r(G)d(CCGG) with a novel intermolecular G-C base-paired quadruplet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

20 March 2017

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

20 March 2017

Chemically modified siRNA: tools and applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Chemical modification: the key to clinical application of RNA interference?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Insights from crystallographic studies into the structural and pairing properties of nucleic acid analogs and chemically modified DNA and RNA oligonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Synthesis and properties of modified siRNA having amide-linked oligoribonucleosides at their 3' overhang regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

RNA interference and chemically modified small interfering RNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Hydration of short DNA, RNA and 2'-OMe oligonucleotides determined by osmotic stressing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Application of circular dichroism to study RNA folding transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Circular dichroism spectroscopy of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

29 September 2017

Absorbance melting curves of RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

2 June 2018

Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

27 November 2018

Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823299

27 November 2018

A highly efficient 24-condition matrix for the crystallization of nucleic acid fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing structural factors stabilizing antisense oligonucleotide duplexes: NMR studies of a DNA.cntdot.DNA duplex containing a formacetal linkage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligoribonucleotide analogues containing a mixed backbone of phosphodiester and formacetal internucleoside linkages, together with vicinal 2'-O-methyl groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solid-phase synthesis of modified RNAs containing amide-linked oligoribonucleosides at their 3'-end and their application to siRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracting thermodynamic data from equilibrium melting curves for oligonucleotide order-disorder transitions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards the structure-based design of oligonucleotide therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hydration, ion release, and excluded volume on the melting of triplex and duplex DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19824732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA904926E

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