(Q27658826)

English

Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors

scientific article

Statements

Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors (English)
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Yu-Sen Wang
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Johannes H Voigt
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Matthew E Kennedy
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Brian M Beyer
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Mary M Senior
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Elizabeth M Smith
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Terry L Nechuta
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Vincent S Madison
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Michael Czarniecki
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Brian A McKittrick
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Andrew W Stamford
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Eric M Parker
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John C Hunter
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William J Greenlee
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Daniel F Wyss
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11 February 2010
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53
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3
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942-50
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Identifiers

 
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