(Q27663325)

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7 February 2020

title

Conserved structural elements in the V3 crown of HIV-1 gp120 (English)

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7 February 2020

6

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7 February 2020

Xiang-Peng Kong

8

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7 February 2020

author name string

Xunqing Jiang

1

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7 February 2020

Valicia Burke

2

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7 February 2020

Maxim Totrov

3

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7 February 2020

Constance Williams

4

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7 February 2020

Timothy Cardozo

5

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7 February 2020

Susan Zolla-Pazner

7

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7 February 2020

publication date

11 July 2010

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Nature Structural & Molecular Biology

7 February 2020

published in

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7 February 2020

volume

17

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7 February 2020

page(s)

955-961

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7 February 2020

issue

8

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

7 February 2020

cites work

1 reference

Identification of a major co-receptor for primary isolates of HIV-1

20 April 2017

1 reference

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

20 April 2017

1 reference

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

20 April 2017

1 reference

Structural definition of a conserved neutralization epitope on HIV-1 gp120

20 April 2017

1 reference

Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity

20 April 2017

1 reference

Structure determination of an anti-HIV-1 Fab 447-52D–peptide complex from an epitaxially twinned data set

20 April 2017

1 reference

Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D

20 April 2017

1 reference

Structural Basis of the Cross-Reactivity of Genetically Related Human Anti-HIV-1 mAbs: Implications for Design of V3-Based Immunogens

20 April 2017

1 reference

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

20 April 2017

1 reference

Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

20 April 2017

1 reference

Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes

20 April 2017

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 April 2017

1 reference

Refinement of macromolecular structures by the maximum-likelihood method

20 April 2017

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

20 April 2017

1 reference

Coot: model-building tools for molecular graphics

20 April 2017

1 reference

Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder

20 April 2017

1 reference

ICM?A new method for protein modeling and design: Applications to docking and structure prediction from the distorted native conformation

20 April 2017

1 reference

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

20 April 2017

1 reference

Basic local alignment search tool

20 April 2017

1 reference

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

20 April 2017

1 reference

Structure of a V3-containing HIV-1 gp120 core

20 April 2017

1 reference

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

20 April 2017

1 reference

The rational design of an AIDS vaccine

20 April 2017

1 reference

Identifying epitopes of HIV-1 that induce protective antibodies

31 March 2020

1 reference

Antibody-based HIV-1 vaccines: recent developments and future directions

31 March 2020

1 reference

Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades.

31 March 2020

1 reference

Molecular switch for alternative conformations of the HIV-1 V3 region: implications for phenotype conversion

31 March 2020

1 reference

Structural basis for coreceptor selectivity by the HIV type 1 V3 loop

31 March 2020

1 reference

Worldwide distribution of HIV type 1 epitopes recognized by human anti-V3 monoclonal antibodies

31 March 2020

1 reference

31 March 2020

V3: HIV's switch-hitter

1 reference

Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant

31 March 2020

1 reference

Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding

31 March 2020

1 reference

Complete nucleotide sequences of functional clones of the AIDS virus

31 March 2020

1 reference

Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity

31 March 2020

1 reference

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein

31 March 2020

1 reference

High prevalence of antibodies to the gp120 V3 region principal neutralizing determinant of HIV-1MN in sera from Africa and the Americas

31 March 2020

1 reference

Antibodies that are cross-reactive for human immunodeficiency virus type 1 clade a and clade B v3 domains are common in patient sera from Cameroon, but their neutralization activity is usually restricted by epitope masking

31 March 2020

1 reference

V3-specific polyclonal antibodies affinity purified from sera of infected humans effectively neutralize primary isolates of human immunodeficiency virus type 1.

31 March 2020

1 reference

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

31 March 2020

1 reference

Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1

31 March 2020

1 reference

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

31 March 2020

1 reference

Cross-clade neutralizing activity of human anti-V3 monoclonal antibodies derived from the cells of individuals infected with non-B clades of human immunodeficiency virus type 1.

31 March 2020

1 reference

Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis

31 March 2020

1 reference

Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1.

31 March 2020

1 reference

Focusing the immune response on the V3 loop, a neutralizing epitope of the HIV-1 gp120 envelope

31 March 2020

1 reference

Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy

31 March 2020

1 reference

Cross-clade neutralizing antibodies against HIV-1 induced in rabbits by focusing the immune response on a neutralizing epitope.

31 March 2020

1 reference

Neutralizing antibody responses to subtype B and C adjuvanted HIV envelope protein vaccination in rabbits

31 March 2020

1 reference

Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates

31 March 2020

1 reference

Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope

31 March 2020

1 reference

Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

31 March 2020

1 reference

Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positio

31 March 2020

1 reference

Immunodominance and antigenic variation of the principal neutralization domain of HIV-1.

31 March 2020

1 reference

The cross-clade neutralizing activity of a human monoclonal antibody is determined by the GPGR V3 motif of HIV type 1

31 March 2020

1 reference

The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

31 March 2020

1 reference

Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein

31 March 2020

1 reference

Random circular permutation of DsbA reveals segments that are essential for protein folding and stability

31 March 2020

1 reference

Systematic circular permutation of an entire protein reveals essential folding elements

31 March 2020

1 reference

Circular permutation analysis as a method for distinction of functional elements in the M20 loop of Escherichia coli dihydrofolate reductase

31 March 2020

1 reference

Roles of HIV-1 Env variable regions in viral neutralization and vaccine development

31 March 2020

1 reference

Generation of human monoclonal antibodies to human immunodeficiency virus

31 March 2020

1 reference

Processing of X-ray diffraction data collected in oscillation mode

31 March 2020

1 reference

Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody

31 March 2020

1 reference

12 December 2020

Improving on nature: focusing the immune response on the V3 loop.

1 reference

12 December 2020

Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120

1 reference

12 December 2020

The majority of neutralizing Abs in HIV-1-infected patients recognize linear V3 loop sequences. Studies using HIV-1MN multiple antigenic peptides

1 reference

12 December 2020

Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity.

1 reference

12 December 2020

Neutralization of primary human immunodeficiency virus type 1 isolates by the broadly reactive anti-V3 monoclonal antibody, 447-52D

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.1861

1 reference

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Dimensions Publication ID

7 February 2020

0 references

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