(Q27664452)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Shigeyuki Yokoyama

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Chafen Lu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Michael J Grey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Jieqing Zhu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Elizabeth Graef

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Timothy A Springer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

13 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

5432-5443

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

Spatial structure of the transmembrane domain heterodimer of ErbB1 and ErbB2 receptor tyrosine kinases

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Spatial structure of the dimeric transmembrane domain of the growth factor receptor ErbB2 presumably corresponding to the receptor active state

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

A transmembrane helix dimer: structure and implications

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

PHENIX: building new software for automated crystallographic structure determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Untangling the ErbB signalling network

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Oncogenic kinase signalling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

ERBB receptors and cancer: the complexity of targeted inhibitors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Spatial control of EGF receptor activation by reversible dimerization on living cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Functional and structural stability of the epidermal growth factor receptor in detergent micelles and phospholipid nanodiscs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Toward high-resolution prediction and design of transmembrane helical protein structures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Biochemical characterization of mutant EGF receptors expressed in the hemopoietic cell line BaF/3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Ligand-induced stimulation of epidermal growth factor receptor mutants with altered transmembrane regions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Use of simian virus 40 replication to amplify Epstein-Barr virus shuttle vectors in human cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Sequence specificity in the dimerization of transmembrane alpha-helices

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Dimerization of the extracellular domain of the receptor for epidermal growth factor containing the membrane-spanning segment in response to treatment with epidermal growth factor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Structural analysis of the transmembrane domain of the epidermal growth factor receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

The single transmembrane domains of ErbB receptors self-associate in cell membranes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976375

De Novo Prediction of Three-dimensional Structures for Major Protein Families

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A dimerization motif for transmembrane α–helices

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00742-10

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20837704%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references