(Q27665343)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20972443%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20972443%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

1

1 reference

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14 January 2020

Ma Xenia G Ilagan

4

1 reference

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14 January 2020

Raphael Kopan

6

1 reference

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14 January 2020

author name string

Matthew Hass

2

1 reference

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14 January 2020

Debbie G McArthur

3

1 reference

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14 January 2020

Jon C Aster

5

1 reference

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14 January 2020

Stephen C Blacklow

7

1 reference

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14 January 2020

publication date

24 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20972443%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

14 January 2020

published in

1 reference

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14 January 2020

volume

17

1 reference

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14 January 2020

issue

11

1 reference

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14 January 2020

page(s)

1312-1317

1 reference

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Thermodynamic and structural insights into CSL-DNA complexes

14 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Version 1.2 of the Crystallography and NMR system

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Presenilin is required for activity and nuclear access of Notch in Drosophila

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Fjx1: a notch-inducible secreted ligand with specific binding sites in developing mouse embryos and adult brain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Notch dimerization is required for leukemogenesis and T-cell development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Ikaros represses the transcriptional response to Notch signaling in T-cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Mutational and energetic studies of Notch 1 transcription complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

A DNA transcription code for cell-specific gene activation by notch signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Notch signaling and inherited disease syndromes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Recognition sequence of a highly conserved DNA binding protein RBP-J kappa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H).

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024583

The suppressor of hairless protein participates in notch receptor signaling

2 June 2018

1 reference

Mastermind is a putative activator for Notch.

21 January 2018

1 reference

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity

21 January 2018

1 reference

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1938

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20972443%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 January 2020

1044727024

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20972443%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

20972443

2 references