(Q27665492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers (English)

1 reference

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15 January 2020

0 references

1

1 reference

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15 January 2020

Alexander F Kintzer

3

1 reference

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15 January 2020

Bryan A. Krantz

8

1 reference

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15 January 2020

author name string

Katie L Thoren

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Harry J Sterling

4

1 reference

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15 January 2020

Iok I Tang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Shoshana G Greenberg

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Evan R Williams

7

1 reference

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15 January 2020

publication date

31 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

15 January 2020

published in

1 reference

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15 January 2020

volume

17

1 reference

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15 January 2020

issue

11

1 reference

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15 January 2020

page(s)

1383-1390

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

15 January 2020

cites work

1 reference

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Structure of a complex of the ATPase SecA and the protein-translocation channel

20 March 2017

1 reference

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

20 March 2017

1 reference

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A model of anthrax toxin lethal factor bound to protective antigen.

20 March 2017

1 reference

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Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

X-ray structure of a protein-conducting channel

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Structure of a Delivery Protein for an AAA+ Protease in Complex with a Peptide Degradation Tag

20 March 2017

1 reference

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Crystal structure of the anthrax lethal factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Crystal structure of the anthrax toxin protective antigen

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

UCSF Chimera--a visualization system for exploratory research and analysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Likelihood-enhanced fast rotation functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Observations on experimental anthrax; demonstration of a specific lethal factor produced in vivo by Bacillus anthracis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Anthrax protective antigen forms oligomers during intoxication of mammalian cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU

20 March 2017

1 reference

https://api.crossref.org/works/10.1038/NSMB.1923

A hot spot of binding energy in a hormone-receptor interface

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Recent developments in the PHENIX software for automated crystallographic structure determination

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Lethal factor unfolding is the most force-dependent step of anthrax toxin translocation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

The 26 S proteasome: from basic mechanisms to drug targeting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Toward an atomic model of the 26S proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Anthrax toxin: receptor binding, internalization, pore formation, and translocation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Protein translocation across biological membranes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Anthrax lethal toxin: a weapon of multisystem destruction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Sculpting the proteome with AAA(+) proteases and disassembly machines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Protein unfolding--an important process in vivo?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Identification of amino acid residues of anthrax protective antigen involved in binding with lethal factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Stoichiometry of anthrax toxin complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Identification of residues lining the anthrax protective antigen channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

GroEL Recognizes an Amphipathic Helix and Binds to the Hydrophobic Side

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Peptide and protein binding in the axial channel of Hsp104. Insights into the mechanism of protein unfolding

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Assembly and disassembly kinetics of anthrax toxin complexes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Mapping the anthrax protective antigen binding site on the lethal and edema factors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Serum protease cleavage of Bacillus anthracis protective antigen

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

The chaperonin GroEL binds a polypeptide in an .alpha.-helical conformation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore

19 June 2018

1 reference

Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine.

21 January 2018

1 reference

Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes.

21 January 2018

1 reference

Protein unfolding by the mitochondrial membrane potential

21 January 2018

1 reference

Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation

21 January 2018

1 reference

Versatile modes of peptide recognition by the AAA+ adaptor protein SspB.

21 January 2018

1 reference

Suite of three protein crystallography beamlines with single superconducting bend magnet as the source.

21 January 2018

1 reference

Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient

21 January 2018

1 reference

Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus

21 January 2018

1 reference

Structural Determinants for the Binding of Anthrax Lethal Factor to Oligomeric Protective Antigen

21 January 2018

1 reference

Mitochondria Unfold Precursor Proteins by Unraveling Them From Their N-termini

21 January 2018

1 reference

Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133606

Basis of Substrate Binding by the Chaperonin GroEL†

27 November 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1923

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 January 2020

1037348056

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21037566%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

21037566

2 references