(Q27666108)

22 June 2017

Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions (English)

1 reference

22 June 2017

0 references

0 references

John E Delorbe

1

1 reference

22 June 2017

John H Clements

series ordinal

2

1 reference

22 June 2017

Benjamin B Whiddon

series ordinal

3

1 reference

22 June 2017

Stephen F Martin

series ordinal

4

1 reference

22 June 2017

1 November 2010

1 reference

ACS Medicinal Chemistry Letters

22 June 2017

1 reference

22 June 2017

1

1 reference

22 June 2017

448-452

1 reference

22 June 2017

8

1 reference

Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization

22 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992351

Conformational constraint in protein ligand design and the inconsistency of binding entropy

29 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21116482

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21116482

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML100142Y

1 reference

22 June 2017

0 references

1 reference