(Q27667321)

English

Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis

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scholarly article

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Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis (English)

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aerotoxic syndrome

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based on heuristic

inferred from title

6

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Jacques-Philippe Colletier

3

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5

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author name string

Eugénie Carletti

1

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Lawrence M Schopfer

2

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Marie-Thérèse Froment

4

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Oksana Lockridge

7

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Patrick Masson

8

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publication date

20 June 2011

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Chemical Research in Toxicology

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24

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6

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797-808

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Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime

1 reference

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Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation

1 reference

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Neuropathy target esterase gene mutations cause motor neuron disease

1 reference

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The toxic effects of triortho-cresyl phosphate on the nervous system; an experimental study in hens

1 reference

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Organophosphorus ester-induced delayed neurotoxicity

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20 March 2017

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PHENIX: building new software for automated crystallographic structure determination

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Neuropathy target esterase

1 reference

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Promotion of organophosphate induced delayed polyneuropathy by certain esterase inhibitors

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The specificity of carboxylesterase protection against the toxicity of organophosphorus compounds

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1 reference

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Development of diagnostics in the search for an explanation of aerotoxic syndrome

1 reference

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29 September 2017

Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos

1 reference

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29 September 2017

Review of tyrosine and lysine as new motifs for organophosphate binding to proteins that have no active site serine

1 reference

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29 September 2017

Organophosphates induce distal axonal damage, but not brain oedema, by inactivating neuropathy target esterase

1 reference

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A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF.

1 reference

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Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates

1 reference

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Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist

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29 September 2017

Model equations for the kinetics of covalent irreversible enzyme inhibition and spontaneous reactivation: esterases and organophosphorus compounds.

1 reference

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29 September 2017

Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry

1 reference

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Mechanism of aging of mipafox-inhibited butyrylcholinesterase

1 reference

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LARGE SCALE PURIFICATION OF BUTYRYLCHOLINESTERASE FROM HUMAN PLASMA SUITABLE FOR INJECTION INTO MONKEYS; A POTENTIAL NEW THERAPEUTIC FOR PROTECTION AGAINST COCAINE AND NERVE AGENT TOXICITY.

1 reference

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Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging

1 reference

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The mipafox-inhibited catalytic domain of human neuropathy target esterase ages by reversible proton loss

1 reference

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Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase

1 reference

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Biological activity of a trio-cresyl phosphate metabolite

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Outbreak of paralysis in Morocco due to ortho-cresyl phosphate poisoning

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The toxicity of commercial jet oils

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Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus

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Hydraulic fluids and jet engine oil: pyrolysis and aircraft air quality

1 reference

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29 September 2017

Aging of phosphylated human acetylcholinesterase: catalytic processes mediated by aromatic and polar residues of the active centre

1 reference

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Plasma cholinesterase variants and the anaesthetist

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Development of insecticidal cyclic phosphoryl compounds through chemical and biochemical approaches

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An evaluation of the inhibition of human butyrylcholinesterase and acetylcholinesterase by the organophosphate chlorpyrifos oxon

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2 June 2018

Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos-oxon.

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Aging of di-isopropyl-phosphorylated human butyrylcholinesterase

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1 reference

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Plasma albumin as a catalyst in cyclization of diaryl o-(α-hydroxy)tolyl phosphates

1 reference

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Acetylcholinesterase. Two types of inhibition by an organophosphorus compound: one the formation of phosphorylated enzyme and the other analogous to inhibition by substrate

1 reference

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Kinetic evidence for thermally induced conformational change of butyrylcholinesterase

1 reference

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1 reference

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A mechanism for organophosphate-induced delayed neuropathy.

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27 November 2018

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https://pubmed.ncbi.nlm.nih.gov/21438623

12 December 2020

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Review of health consequences from high-, intermediate- and low-level exposure to organophosphorus nerve agents

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Human butyrylcholinesterase as a general prophylactic antidote for nerve agent toxicity. In vitro and in vivo quantitative characterization

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The influence of 2-/o-cresyl/-4 H-1 : 3 : 2-benzodioxa-phosphorin-2-oxide (CBDP) on organophosphate poisoning and its therapy

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https://pubmed.ncbi.nlm.nih.gov/21438623

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Large-scale purification and long-term stability of human butyrylcholinesterase: a potential bioscavenger drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/21438623

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/TX100447K

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