(Q27671551)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

main subject

1 reference

GeneDB

5 February 2019

1 reference

GeneDB

6 February 2019

0 references

0 references

0 references

1

1 reference

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9 February 2020

Ricardo Silvestre

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

Anabela Cordeiro-da-Silva

9 February 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Denis Sereno

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Baptiste Vergnes

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jean-François Guichou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Gilles Labesse

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

D Garcia

2

1 reference

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9 February 2020

C Gérard

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

M Seveno

7

1 reference

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9 February 2020

A Ouaissi

9

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

1 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

published in

Molecular Microbiology

1 reference

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9 February 2020

volume

82

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

1

1 reference

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9 February 2020

page(s)

21-38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21819459%20AND%20SRC:MED&resulttype=core&format=json

Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome

9 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Protein turnover and differentiation in Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Life in vacuoles--nutrient acquisition by Leishmania amastigotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Global gene expression in Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

In vitro sensitivity testing of Leishmania clinical field isolates: preconditioning of promastigotes enhances infectivity for macrophage host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Initial characterization of a recombinant kynureninase from Trypanosoma cruzi identified from an EST database.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Sequence analysis of small subunit ribosomal RNA genes and its use for detection and identification of Leishmania parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

High-Resolution Crystal Structures of Streptococcus pneumoniae Nicotinamidase with Trapped Intermediates Provide Insights into the Catalytic Mechanism and Inhibition by Aldehydes,

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Specificity and Mechanism ofAcinetobacter baumaniiNicotinamidase: Implications for Activation of the Front-Line Tuberculosis Drug Pyrazinamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

In vitro activity of nicotinamide/antileishmanial drug combinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Crystal structure of the yeast nicotinamidase Pnc1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

The genome of the kinetoplastid parasite, Leishmania major

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Brucella abortus nicotinamidase (PncA) contributes to its intracellular replication and infectivity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages: the Leishmania genome is constitutively expressed.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Assimilation of NAD(+) precursors in Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

High-affinity transporters for NAD+ precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Pnc1p-mediated nicotinamide clearance modifies the epigenetic properties of rDNA silencing in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Living in a phagolysosome; metabolism of Leishmania amastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Host-parasite interactions revealed by Plasmodium falciparum metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Genetic structure of the nadA and nadB antivirulence loci in Shigella spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Reconstructing eukaryotic NAD metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Kinetics and inhibition of nicotinamidase from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

In vitro antileishmanial activity of nicotinamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Advances in the treatment of leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Molecular replacement with MOLREP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

NAD+ auxotrophy is bacteriocidal for the tubercle bacilli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X

PRIMUS: a Windows PC-based system for small-angle scattering data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07799.X