(Q27677190)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Structure and allostery of the PKA RIIβ tetrameric holoenzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

Protein kinase, cAMP dependent regulatory, type II beta

22 January 2020

main subject

1 reference

Protein kinase, cAMP dependent, catalytic, alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Alexandr P Kornev

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Ping Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Eric V Smith-Nguyen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Malik M Keshwani

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Michael S Deal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Susan S Taylor

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

712-716

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

6069

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα Holoenzyme

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Novel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme Structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Contribution of Non-catalytic Core Residues to Activity and Regulation in Protein Kinase A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

PKA Type II Holoenzyme Reveals a Combinatorial Strategy for Isoform Diversity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

The protein kinase complement of the human genome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Phosphorylation of the cAMP-dependent protein kinase (PKA) regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation, and calcium signaling in cardiac cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

AKAP signaling complexes: getting to the heart of the matter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

The cAMP binding domain: an ancient signaling module

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Dynamics of cAMP-dependent protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Mobilization of the A-kinase N-myristate through an isoform-specific intermolecular switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Mutation of the RIIbeta subunit of protein kinase A prevents diet-induced insulin resistance and dyslipidemia in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3985767

Differential binding of cAMP-dependent protein kinase regulatory subunit isoforms Ialpha and IIbeta to the catalytic subunit

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Classification and phylogenetic analysis of the cAMP-dependent protein kinase regulatory subunit family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Type II beta regulatory subunit of cAMP-dependent protein kinase: purification strategies to optimize crystallization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Backbone flexibility of five sites on the catalytic subunit of cAMP-dependent protein kinase in the open and closed conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Determination of domain structure of proteins from X-ray solution scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Molecular basis for isoform-specific autoregulation of protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213979

Physiological inhibitors of the catalytic subunit of cAMP-dependent protein kinase: effect of magnesium-ATP on protein-protein interactions

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22323819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Snapping of the carboxyl terminal tail of the catalytic subunit of PKA onto its core: characterization of the sites by mutagenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22323819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1213979

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

release_fdgv6atayjhh3nkmmkzppzo32q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fdgv6atayjhh3nkmmkzppzo32q

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22323819%20AND%20SRC:MED&resulttype=core&format=json