(Q27678743)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

The 1.8 Å cholix toxin crystal structure in complex with NAD+ and evidence for a new kinetic model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

0 references

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Robert J Fieldhouse

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Miguel R Lugo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

A Rod Merrill

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

25 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

21176-21188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939

30 January 2020

cites work

1 reference

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Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase Toxins

20 March 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

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Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins

20 March 2017

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Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa from Clostridium difficile

20 March 2017

1 reference

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The nature and character of the transition state for the ADP-ribosyltransferase reaction

20 March 2017

1 reference

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Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae

20 March 2017

1 reference

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Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

20 March 2017

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Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase

20 March 2017

1 reference

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Substrate binding and catalysis of ecto-ADP-ribosyltransferase 2.2 from rat

20 March 2017

1 reference

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The crystal structure of C3stau2 from Staphylococcus aureus and its complex with NAD

20 March 2017

1 reference

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Crystal structure and site-directed mutagenesis of enzymatic components from Clostridium perfringens iota-toxin

20 March 2017

1 reference

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Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Electrostatics of nanosystems: application to microtubules and the ribosome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Structural basis for the activation of cholera toxin by human ARF6-GTP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Diversity and distribution of cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae

20 March 2017

1 reference

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Therapeutic potential of anticancer immunotoxins.

29 September 2017

1 reference

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From cosubstrate similarity to inhibitor diversity--inhibitors of ADP-ribosyltransferases from kinase inhibitor screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

A role for flexible loops in enzyme catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity

29 September 2017

1 reference

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Developing novel approaches to improve binding energy estimation and virtual screening: a PARP case study

29 September 2017

1 reference

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Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins

29 September 2017

1 reference

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Putative virulence traits and pathogenicity of Vibrio cholerae Non-O1, Non-O139 isolates from surface waters in Kolkata, India

29 September 2017

1 reference

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The biology and future prospects of antivirulence therapies

29 September 2017

1 reference

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Immunotoxin treatment of cancer

29 September 2017

1 reference

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The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry

29 September 2017

1 reference

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Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme

29 September 2017

1 reference

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A glimpse into the expanded genome content of Vibrio cholerae through identification of genes present in environmental strains

29 September 2017

1 reference

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Application of microbial genomic science to advanced therapeutics

29 September 2017

1 reference

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Investigation into the catalytic role for the tryptophan residues within domain III of Pseudomonas aeruginosa exotoxin A.

29 September 2017

1 reference

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Expression of Enzymic Activity by Exotoxin A from Pseudomonas aeruginosa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Dynamic and static quenching of 1,N6-ethenoadenine fluorescence in nicotinamide 1,N6-ethenoadenine dinucleotide and in 1,N6-etheno-9-(3-(indol-3-yl) propyl) adenine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Processing of Pseudomonas aeruginosa exotoxin A is dispensable for cell intoxication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

A steric antagonism of actin polymerization by a salmonella virulence protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Linking distinct conformations of nicotinamide adenine dinucleotide with protein fold/function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Molecular complexes at a glance: automated generation of two-dimensional complex diagrams.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Application of a fluorometric assay for characterization of the catalytic competency of a domain III fragment of Pseudomonas aeruginosa exotoxin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

A catalytic loop within Pseudomonas aeruginosa exotoxin A modulates its transferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Insight into the catalytic mechanism of Pseudomonas aeruginosa exotoxin A. Studies of toxin interaction with eukaryotic elongation factor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Protein-protein interaction using tryptophan analogues: novel spectroscopic probes for toxin-elongation factor-2 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337311

Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375540

A fluorescence investigation of the active site of Pseudomonas aeruginosa exotoxin A

27 November 2018

1 reference

12 December 2020

Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis

1 reference

12 December 2020

Novel poly(ADP-ribose) polymerase-1 inhibitors

1 reference

12 December 2020

LigAlign: flexible ligand-based active site alignment and analysis

1 reference

12 December 2020

Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.337311

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

release_35mh2pdegnhh3a5747eocihvw4

30 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/35mh2pdegnhh3a5747eocihvw4

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535961%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

22535961

1 reference