(Q27679169)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Structural insights into human peroxisome proliferator activated receptor delta (PPAR-delta) selective ligand binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

Ana Carolina M Figueira

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Igor Polikarpov

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Fernanda A H Batista

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Daniela B B Trivella

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Amanda Bernardes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Joyce Gratieri

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Paulo S L Oliveira

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Paul Webb

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

11 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

e33643

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 February 2020

copyright license

start time

11 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

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Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

20 March 2017

1 reference

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The MX2 macromolecular crystallography beamline: a wiggler X-ray source at the LNLS

20 March 2017

1 reference

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Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents

20 March 2017

1 reference

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Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Phasercrystallographic software

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

The PPARs: from orphan receptors to drug discovery

20 March 2017

1 reference

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Peroxisome proliferator-activated receptors: nuclear control of metabolism

20 March 2017

1 reference

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Infrastructure for the life sciences: design and implementation of the UniProt website

20 March 2017

1 reference

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350516

Peroxisome proliferator-activated receptor beta stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin

29 September 2017

1 reference

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Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis

29 September 2017

1 reference

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Pharmacological activation of PPARbeta promotes rapid and calcineurin-dependent fiber remodeling and angiogenesis in mouse skeletal muscle

29 September 2017

1 reference

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PPARgamma in human and mouse physiology

29 September 2017

1 reference

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Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

29 September 2017

1 reference

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An overview on biological mechanisms of PPARs.

29 September 2017

1 reference

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity

29 September 2017

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Roles of PPARs in health and disease.

29 September 2017

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29 September 2017

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Recombinant human PPAR-beta/delta ligand-binding domain is locked in an activated conformation by endogenous fatty acids.

2 June 2018

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Important pharmacophoric features of pan PPAR agonists: common chemical feature analysis and virtual screening.

21 January 2018

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Set-up and experimental parameters of the protein crystallography beamline at the Brazilian National Synchrotron Laboratory.

21 January 2018

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Pharmacophore modeling and parallel screening for PPAR ligands

21 January 2018

1 reference

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10.1371/JOURNAL.PONE.0033643

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22606221%20AND%20SRC:MED&resulttype=core&format=json