(Q27681059)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

Erratum: Corrigendum: The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks

4 February 2020

main subject

structural biology

0 references

corrigendum / erratum

0 references

author

Raquel Arribas-Bosacoma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Marek Kozlowski

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Markus Hassler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Laurence Pearl

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Antony W. Oliver

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Ammar A E Ali

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Gyula Timinszky

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Paul O Hassa

5

1 reference

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4 February 2020

Andreas G Ladurner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

publication date

10 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

4 February 2020

published in

1 reference

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4 February 2020

volume

19

1 reference

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4 February 2020

issue

7

1 reference

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4 February 2020

page(s)

685-692

1 reference

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Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

4 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

The macro domain is an ADP-ribose binding module

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

Solving structures of protein complexes by molecular replacement with Phaser

22 April 2017

1 reference

Coot: model-building tools for molecular graphics

22 April 2017

1 reference

MolProbity: all-atom structure validation for macromolecular crystallography

22 April 2017

1 reference

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

7 April 2017

1 reference

Histone ADP-ribosylation in DNA repair, replication and transcription.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

PARP1 ADP-ribosylates lysine residues of the core histone tails

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Uncoupling of the transactivation and transrepression functions of PARP1 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Structural and biophysical studies of human PARP-1 in complex with damaged DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Parthanatos, a messenger of death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Analysis of nucleotide sequence-dependent DNA binding of poly(ADP-ribose) polymerase in a purified system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Poly(ADP-ribose) polymerase-1 dimerizes at a 5' recessed DNA end in vitro: a fluorescence study.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Receptor kinase signalling in plants and animals: distinct molecular systems with mechanistic similarities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Role of heparan sulfate in fibroblast growth factor signalling: a structural view

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Poly(ADP-ribose) polymerase: a molecular nick-sensor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Inhibition of homodimerization of poly(ADP-ribose) polymerase by its C-terminal cleavage products produced during apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Macromolecular association of ADP-ribosyltransferase and its correlation with enzymic activity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Histone H1 poly[ADP]-ribosylation regulates the chromatin alterations required for learning consolidation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Regulation of poly(ADP-ribose) polymerase-1 by DNA structure-specific binding

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Activity assays for poly-ADP ribose polymerase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826610

DNA-induced dimerization of poly(ADP-ribose) polymerase-1 triggers its activation

27 November 2018

1 reference

Release of core DNA from nucleosomal core particles following (ADP-ribose)n-modification in vitro

31 March 2020

1 reference

DNA strand break-mediated partitioning of poly(ADP-ribose) polymerase function

31 March 2020

1 reference

Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions

31 March 2020

1 reference

Specific binding of poly(ADP-ribose) polymerase-1 to cruciform hairpins

31 March 2020

1 reference

Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway

31 March 2020

1 reference

Recent developments in the PHENIX software for automated crystallographic structure determination

31 March 2020

1 reference

Determination of poly(ADP-ribose) chain length distribution on polyacrylamide gels by silver staining

31 March 2020

1 reference

Poly(ADP-ribose) quantification at the femtomole level in mammalian cells

31 March 2020

1 reference

Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction is intermolecular

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22683995

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2335

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 February 2020

1021212361

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

22683995

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22683995%20AND%20SRC:MED&resulttype=core&format=json