(Q27682069)

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Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through [...]

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10 March 2020

Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer (English)

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10 March 2020

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Trypanosoma cruzi

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Alejandro Buschiazzo

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10 March 2020

Carlos Batthyany

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10 March 2020

Marcelo A. Marti

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10 March 2020

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Alejandra Martinez

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10 March 2020

Gonzalo Peluffo

2

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Ariel A Petruk

3

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Dolores Piñeyro

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Verónica Demicheli

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10 March 2020

Analía Lima

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Rosario Durán

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10 March 2020

Nicole Larrieux

13

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Rafael Radi

16

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10 March 2020

Lucía Piacenza

17

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10 March 2020

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10 March 2014

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10 March 2020

Journal of Biological Chemistry

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10 March 2020

289

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10 March 2020

12760-12778

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10 March 2020

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20 March 2017

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20 March 2017

Systematic structural studies of iron superoxide dismutases from human parasites and a statistical coupling analysis of metal binding specificity

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7 April 2017

Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34

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20 March 2017

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20 March 2017

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20 March 2017

Tissue sulfhydryl groups

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20 March 2017

Nitration of solvent-exposed tyrosine 74 on cytochrome c triggers heme iron-methionine 80 bond disruption. Nuclear magnetic resonance and optical spectroscopy studies

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20 March 2017

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20 March 2017

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20 March 2017

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7 April 2017

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29 September 2017

Peroxynitrite, a stealthy biological oxidant

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Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins

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29 September 2017

Molecular basis of intramolecular electron transfer in proteins during radical-mediated oxidations: computer simulation studies in model tyrosine-cysteine peptides in solution

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29 September 2017

Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51)

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29 September 2017

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Peroxynitrite mediates active site tyrosine nitration in manganese superoxide dismutase. Evidence of a role for the carbonate radical anion

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Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence

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29 September 2017

Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite

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29 September 2017

Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration

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29 September 2017

Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts

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29 September 2017

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29 September 2017

Manganese and iron superoxide dismutases are structural homologs

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29 September 2017

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

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29 September 2017

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2 June 2018

Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

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2 June 2018

Superoxide dismutase: a comparison of rate constants.

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2 June 2018

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2 June 2018

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2 June 2018

Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine.

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21 January 2018

Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase

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21 January 2018

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21 January 2018

Tryparedoxin peroxidases and superoxide dismutases expression as well as ROS release are related to Trypanosoma cruzi epimastigotes growth phases.

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21 January 2018

Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals

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21 January 2018

The N-pentenoyl protecting group for aminoacyl-tRNAs

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21 January 2018

Improved Treatment of Ligands and Coupling Effects in Empirical Calculation and Rationalization of pKa Values.

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21 January 2018

Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite.

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21 January 2018

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21 January 2018

Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite.

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21 January 2018

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21 January 2018

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21 January 2018

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa Predictions

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21 January 2018

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27 November 2018

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27 November 2018

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27 November 2018

Influence of amino acid side chains on long-distance electron transfer in peptides: electron hopping via "stepping stones"

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12 December 2020

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Kinetics of peroxynitrite reaction with amino acids and human serum albumin

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12 December 2020

based on heuristic

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Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite

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12 December 2020

based on heuristic

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The catalytic role of carbon dioxide in the decomposition of peroxynitrite

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12 December 2020

based on heuristic

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A modified version of the Cornell et al. force field with improved sugar pucker phases and helical repeat

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12 December 2020

based on heuristic

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Exploring the molecular basis of human manganese superoxide dismutase inactivation mediated by tyrosine 34 nitration

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12 December 2020

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Spin labeling of protein sulfhydryl groups by spin trapping a sulfur radical: Application to bovine serum albumin and myosin

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide

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12 December 2020

based on heuristic

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12 December 2020

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12 December 2020

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12 December 2020

based on heuristic

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12 December 2020

based on heuristic

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Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron-tunneling pathways in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Nitric-oxide Synthase Stimulation Causes CytochromecRelease from Isolated Mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mitochondrial electron transport by peroxynitrite

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo rat hemoglobin thiyl free radical formation following administration of phenylhydrazine and hydrazine-based drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A possible role for the species peroxonitrite in intrification

1 reference

https://pubmed.ncbi.nlm.nih.gov/24616096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.545590

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24616096%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24616096%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24616096%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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