(Q27683752)

English

The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition

scientific article

Statements

The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition (English)
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Xun Zhao
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Dagart Allison
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Bradley Condon
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Feiyu Zhang
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Tarun Gheyi
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Aiping Zhang
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Sheela Ashok
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Marijane Russell
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Iain MacEwan
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Yuewei Qian
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James A Jamison
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John Gately Luz
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14 February 2013
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56
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3
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963-9
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