(Q27684181)

12

1 reference

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7 June 2020

Paul N. Mortenson

16

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7 June 2020

author name string

Steven Howard

1

1 reference

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7 June 2020

Nader Amin

2

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7 June 2020

Andrew B Benowitz

3

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7 June 2020

Elisabetta Chiarparin

4

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7 June 2020

Haifeng Cui

5

1 reference

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7 June 2020

Xiaodong Deng

6

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7 June 2020

Tom D Heightman

7

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7 June 2020

David J Holmes

8

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7 June 2020

Anna Hopkins

9

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7 June 2020

Jianzhong Huang

10

1 reference

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7 June 2020

Qi Jin

11

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7 June 2020

Agnes C L Martin

13

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7 June 2020

Frances Massey

14

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7 June 2020

Lynn McCloskey

15

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7 June 2020

Puja Pathuri

17

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7 June 2020

Dominic Tisi

18

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7 June 2020

Pamela A Williams

19

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ACS Medicinal Chemistry Letters

7 June 2020

publication date

12 December 2013

0 references

published in

2 references

Crossref

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7 June 2020

volume

4

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7 June 2020

issue

12

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7 June 2020

page(s)

1208-1212

1 reference

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Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

7 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In Vivo

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Structure of the adenylation domain of NAD+-dependent DNA ligase fromStaphylococcus aureus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Drugs for bad bugs: confronting the challenges of antibacterial discovery

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Ligand efficiency: a useful metric for lead selection

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Experiences in fragment-based drug discovery

7 April 2017

1 reference

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The rise of fragment-based drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Discovery and design of DNA and RNA ligase inhibitors in infectious microorganisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

DNA ligases: progress and prospects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

In vitro and in vivo validation of ligA and tarI as essential targets in Staphylococcus aureus

29 September 2017

1 reference

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DNA ligases: structure, reaction mechanism, and function

29 September 2017

1 reference

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DNA ligase: structure, mechanism, and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Assessing the lipophilicity of fragments and early hits.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Characterization of a temperature-sensitive DNA ligase from Escherichia coli

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027552

Discovery of bacterial NAD+-dependent DNA ligase inhibitors: optimization of antibacterial activity

27 November 2018

1 reference

12 December 2020

Physicochemical properties of antibacterial compounds: implications for drug discovery

1 reference

12 December 2020

Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery

1 reference

12 December 2020

Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part 2: 4-amino-pyrido[2,3-d]pyrimidin-5(8H)-ones

1 reference

12 December 2020

Identifiers

DOI

10.1021/ML4003277

2 references

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7 June 2020

1 reference

2 references

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7 June 2020

2 references