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Structure, mechanism, and substrate specificity of kynureninase
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title
Structure, mechanism, and substrate specificity of kynureninase
(English)
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author name string
Robert S. Phillips
series ordinal
1
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language of work or name
English
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publication date
November 2011
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PubMed
published in
Biochimica et Biophysica Acta
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PubMed
volume
1814
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PubMed
issue
11
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PubMed
page(s)
1481-8
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PubMed
cites work
Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity
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PubMed Central
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20 March 2017
Crystal structure of Homo sapiens kynureninase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102132
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20 March 2017
Three-dimensional structure of kynureninase from Pseudomonas fluorescens
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PubMed Central
reference URL
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20 March 2017
Proinflammatory cytokine interferon-gamma increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid beta peptide 1-42: implications for the pathogenesis of Alzheimer's disease
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29 September 2017
Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease
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Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis
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Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects
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Cloning, sequence, and expression of kynureninase from Pseudomonas fluorescens
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29 September 2017
Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients
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29 September 2017
Substituent effects on the reaction of beta-benzoylalanines with Pseudomonas fluorescens kynureninase
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Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors
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2 June 2018
Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step
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2 June 2018
The catalytic mechanism of kynureninase from Pseudomonas fluorescens: evidence for transient quinonoid and ketimine intermediates from rapid-scanning stopped-flow spectrophotometry
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Kynurenine disposition in blood and brain of mice: effects of selective inhibitors of kynurenine hydroxylase and of kynureninase.
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From oxygenase to sleep
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Kynurenine metabolism in multiple sclerosis.
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27 November 2018
The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction
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PubMed Central
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27 November 2018
Differential effects of bromination on substrates and inhibitors of kynureninase from Pseudomonas fluorescens
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102132
retrieved
27 November 2018
2-Amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic acid; a potent inhibitor of rat and recombinant human kynureninase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102132
retrieved
27 November 2018
The catalytic mechanism of kynureninase from Pseudomonas fluorescens: insights from the effects of pH and isotopic substitution on steady-state and pre-steady-state kinetics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102132
retrieved
27 November 2018
Homology of pyridoxal-5'-phosphate-dependent aminotransferases with the cobC (cobalamin synthesis), nifS (nitrogen fixation), pabC (p-aminobenzoate synthesis) and malY (abolishing endogenous induction of the maltose system) gene products.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102132
retrieved
27 November 2018
Crystalline kynureninase from Pseudomonas marginalis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21167323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of beta-carbanion formation during kynurenine hydrolysis catalyzed by Pseudomonas marginalis kynureninase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21167323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
S-aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21167323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The kynureninase of Pseudomonas fluorescens
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21167323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBAPAP.2010.12.003
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
160371
OpenCitations bibliographic resource ID
160371
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
160371
PMC publication ID
3102132
1 reference
stated in
PubMed
PubMed publication ID
21167323
1 reference
stated in
PubMed
ResearchGate publication ID
49692073
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