(Q27689325)

7

0 references

author name string

Xiaohua Lou

1

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Gudrun Toresson

2

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Cindy Benod

3

0 references

Ji Ho Suh

4

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Kevin J Philips

5

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Paul Webb

Nature Structural & Molecular Biology

6

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language of work or name

English

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publication date

March 2014

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published in

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volume

21

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page(s)

277-81

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issue

3

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cites work

Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA

1 reference

Multidomain integration in the structure of the HNF-4α nuclear receptor complex

22 April 2017

1 reference

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

22 April 2017

1 reference

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

22 April 2017

1 reference

Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression

22 April 2017

1 reference

Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA

22 April 2017

1 reference

Structural determinants of nuclear receptor assembly on DNA direct repeats

22 April 2017

1 reference

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity

22 April 2017

1 reference

PHENIX: a comprehensive Python-based system for macromolecular structure solution

22 April 2017

1 reference

Nuclear receptors and lipid physiology: opening the X-files

22 April 2017

1 reference

The nuclear receptor superfamily: a rosetta stone for physiology

22 April 2017

1 reference

Orphan nuclear receptors: shifting endocrinology into reverse

21 January 2018

1 reference

Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics

21 January 2018

1 reference

LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function

21 January 2018

1 reference

LXRs regulate the balance between fat storage and oxidation.

21 January 2018

1 reference

Separate and overlapping metabolic functions of LXRalpha and LXRbeta in C57Bl/6 female mice

21 January 2018

1 reference

Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity

21 January 2018

1 reference

Genome-wide expression profiling; a panel of mouse tissues discloses novel biological functions of liver X receptors in adrenals.

21 January 2018

1 reference

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

21 January 2018

1 reference

A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor

21 January 2018

1 reference

The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration

21 January 2018

1 reference

Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity

21 January 2018

1 reference

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation

21 January 2018

1 reference

Activation of the liver X receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy

21 January 2018

1 reference

Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism.

21 January 2018

1 reference

Liver X receptors inhibit proliferation of human colorectal cancer cells and growth of intestinal tumors in mice

21 January 2018

1 reference

Central diabetes insipidus associated with impaired renal aquaporin-1 expression in mice lacking liver X receptor β

21 January 2018

1 reference

Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons

21 January 2018

1 reference

Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia

21 January 2018

1 reference

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells

21 January 2018

1 reference

Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease

21 January 2018

1 reference

Liver X receptor biology and pharmacology: new pathways, challenges and opportunities.

21 January 2018

1 reference

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

21 January 2018

2 references

https://pubmed.ncbi.nlm.nih.gov/24561505

21 January 2018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Constitutive androstane receptor transactivates the hepatic expression of mouse Dhcr24 and human DHCR24 encoding a cholesterogenic enzyme 24-dehydrocholesterol reductase

1 reference

The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.

21 January 2018

1 reference

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

21 January 2018

1 reference

Nuclear-receptor interactions on DNA-response elements

21 January 2018

1 reference

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

21 January 2018

1 reference

Low-resolution molecular models reveal the oligomeric state of the PPAR and the conformational organization of its domains in solution

21 January 2018

1 reference

Low resolution structures of the retinoid X receptor DNA-binding and ligand-binding domains revealed by synchrotron X-ray solution scattering.

21 January 2018

1 reference

Structural determinants of allosteric ligand activation in RXR heterodimers.

21 January 2018

1 reference

Ligand control of coregulator recruitment to nuclear receptors

21 January 2018

1 reference

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Nuclear receptors, inflammation, and neurodegenerative diseases

21 January 2018

1 reference

Orphan receptors chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and retinoid X receptor (RXR) activate and bind the rat cholesterol 7alpha-hydroxylase gene (CYP7A)

31 March 2020

1 reference

Low-resolution structures of thyroid hormone receptor dimers and tetramers in solution

31 March 2020

1 reference

Separation of the hormone- and DNA-binding sites of the hepatic glucocorticoid receptor by means of proteolysis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24561505