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Genetically determined epithelial dysfunction and its consequences for microflora-host interactions
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scholarly article
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PubMed
title
Genetically determined epithelial dysfunction and its consequences for microflora-host interactions
(English)
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stated in
PubMed
author name string
Kaser A
series ordinal
1
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PubMed
Niederreiter L
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2
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PubMed
Blumberg RS
series ordinal
3
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PubMed
publication date
November 2011
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PubMed
published in
Cellular and Molecular Life Sciences
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PubMed
volume
68
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PubMed
issue
22
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PubMed
page(s)
3643-9
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PubMed
cites work
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
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PubMed Central
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Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
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PubMed Central
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20 March 2017
Homeostasis and inflammation in the intestine
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PubMed Central
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20 March 2017
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
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PubMed Central
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20 March 2017
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
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PubMed Central
reference URL
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20 March 2017
Reduced Paneth cell alpha-defensins in ileal Crohn's disease
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PubMed Central
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20 March 2017
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
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PubMed Central
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20 March 2017
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
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PubMed Central
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20 March 2017
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
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PubMed Central
reference URL
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20 March 2017
Autophagy fights disease through cellular self-digestion
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PubMed Central
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20 March 2017
Autophagy in the Pathogenesis of Disease
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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20 March 2017
Signal integration in the endoplasmic reticulum unfolded protein response
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PubMed Central
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20 March 2017
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
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PubMed Central
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20 March 2017
Induction of intestinal Th17 cells by segmented filamentous bacteria
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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20 March 2017
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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20 March 2017
Stem cells, self-renewal, and differentiation in the intestinal epithelium
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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20 March 2017
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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20 March 2017
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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20 March 2017
The mammalian unfolded protein response
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
Inflammatory bowel disease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
retrieved
7 April 2017
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
Regulation and function of NF-kappaB transcription factors in the immune system
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
A microbial symbiosis factor prevents intestinal inflammatory disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
retrieved
7 April 2017
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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7 April 2017
Host-bacterial symbiosis in health and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
Paneth cells and innate mucosal immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
retrieved
29 September 2017
Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
Sensing the outside world: TSLP regulates barrier immunity.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
Enteric defensins are essential regulators of intestinal microbial ecology
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
The endoplasmic reticulum stress response in immunity and autoimmunity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
Chronic stimulation of Nod2 mediates tolerance to bacterial products
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592146
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29 September 2017
Bacterial colonization leads to the colonic secretion of RELMβ/FIZZ2, a novel goblet cell-specific protein
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PubMed Central
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29 September 2017
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
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PubMed Central
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29 September 2017
Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains
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PubMed Central
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2 June 2018
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
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21 January 2018
Non-apoptotic role of BID in inflammation and innate immunity.
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27 November 2018
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
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21 January 2018
Epithelial NEMO links innate immunity to chronic intestinal inflammation
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21 January 2018
Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk
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12 December 2020
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Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/21984606
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21984606
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S00018-011-0827-Y
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Dimensions Publication ID
1035319432
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PMC publication ID
4592146
1 reference
stated in
PubMed
PubMed publication ID
21984606
1 reference
stated in
PubMed
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