(Q27704829)

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Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies

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scholarly article

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Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies (English)

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1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

lymphoblastic leukemia

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based on heuristic

inferred from title

T-cell acute lymphoblastic leukemia

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based on heuristic

inferred from title

author name string

P Bernasconi-Elias

1

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T Hu

2

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D Jenkins

3

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B Firestone

4

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S Gans

5

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E Kurth

6

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P Capodieci

7

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J Deplazes-Lauber

8

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K Petropoulos

9

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P Thiel

10

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D Ponsel

11

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S Hee Choi

12

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P LeMotte

13

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A London

14

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M Goetcshkes

15

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E Nolin

16

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M D Jones

17

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K Slocum

18

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M J Kluk

19

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D M Weinstock

20

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A Christodoulou

21

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O Weinberg

22

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J Jaehrling

23

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S A Ettenberg

24

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A Buckler

25

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S C Blacklow

26

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J C Aster

27

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C J Fryer

28

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language of work or name

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publication date

9 May 2016

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From fly wings to targeted cancer therapies: a centennial for notch signaling

1 reference

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20 March 2017

Integrated genomic analyses of ovarian carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Therapeutic antibody targeting of individual Notch receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

RNA-Seq: a revolutionary tool for transcriptomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Structural basis for autoinhibition of Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Announcing the worldwide Protein Data Bank

1 reference

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20 March 2017

Essential role of endothelial Notch1 in angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

20 March 2017

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

7 April 2017

The canonical Notch signaling pathway: unfolding the activation mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

7 April 2017

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

7 April 2017

Osteoblastic cells regulate the haematopoietic stem cell niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

7 April 2017

Notch signaling is essential for vascular morphogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

7 April 2017

Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Whole exome sequencing of adenoid cystic carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

The mutational landscape of adenoid cystic carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

The Notch signalling system: recent insights into the complexity of a conserved pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Targeting the Notch pathway: twists and turns on the road to rational therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Notch signaling: simplicity in design, versatility in function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Notch: architect, landscaper, and guardian of the intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Notch signalling in solid tumours: a little bit of everything but not all the time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Microdroplet-based PCR enrichment for large-scale targeted sequencing

1 reference

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29 September 2017

Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

1 reference

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29 September 2017

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

29 September 2017

Insights into Notch3 activation and inhibition mediated by antibodies directed against its negative regulatory region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5102827

2 June 2018

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.133

21 January 2018

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.133

21 January 2018

Amplicon profiles in ovarian serous carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.133

31 March 2020

Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.133

31 March 2020

Identifiers

10.1038/ONC.2016.133

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Dimensions Publication ID

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Springer Nature article ID

10.1038/onc.2016.133

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