(Q27729459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7552725%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

title

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase (English)

1 reference

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20 October 2019

0 references

0 references

2

1 reference

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20 October 2019

author name string

Loll PJ

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7552725%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

Garavito RM

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7552725%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

publication date

1 August 1995

1 reference

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Nature structural biology

20 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7552725%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

volume

2

1 reference

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20 October 2019

issue

8

1 reference

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20 October 2019

page(s)

637-643

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7552725%20AND%20SRC:MED&resulttype=core&format=json

The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

20 October 2019

cites work

1 reference

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21 April 2017

1 reference

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 April 2017

1 reference

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Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

21 April 2017

1 reference

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Mutation of serine-516 in human prostaglandin G/H synthase-2 to methionine or aspirin acetylation of this residue stimulates 15-R-HETE synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSB0895-637

A model for the catalytic mechanism of prostaglandin endoperoxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSB0895-637

Structural requirements for preventing the aspirin- and the arachidonate-induced inactivation of platelet cyclo-oxygenase: additional evidence for distinct enzymatic sites

21 January 2018

1 reference

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Pharmacology of platelet inhibition in humans: implications of the salicylate-aspirin interaction

21 January 2018

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The inhibition of cyclo-oxygenase of rabbit platelets by aspirin is prevented by salicylic acid and by phenanthrolines

21 January 2018

1 reference

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Non-steroidal anti-inflammatory drugs react with two sites on platelet cyclo-oxygenase evidence from ‘in vivo’ drug interaction studies in rats

21 January 2018

1 reference

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Acetylation of prostaglandin synthase by aspirin

21 January 2018

1 reference

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Isolation and covalent structure of the aspirin-modified, active-site region of prostaglandin synthetase

31 March 2020

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Tyrosyl radicals and their role in hydroperoxide-dependent activation and inactivation of prostaglandin endoperoxide synthase

31 March 2020

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Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs

31 March 2020

1 reference

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Multiple sites on prostaglandin cyclooxygenase are determinants in the action of nonsteroidal antiinflammatory agents

31 March 2020

1 reference

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Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects

31 March 2020

1 reference

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Salicylate reverses in vitro aspirin inhibition of rat platelet and vascular prostaglandin generation

31 March 2020

1 reference

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Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

31 March 2020

1 reference

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