(Q27730413)

English

Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers

scientific article

In more languages

Statements

scholarly article

0 references

Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers (English)

0 references

1 reference

based on heuristic

inferred from title

crystallography

1 reference

based on heuristic

inferred from title

author name string

W S Lewis

1

0 references

V Cody

2

0 references

N Galitsky

3

0 references

J R Luft

4

0 references

W Pangborn

5

0 references

S K Chunduru

6

0 references

H T Spencer

7

0 references

J R Appleman

8

0 references

R L Blakley

9

0 references

language of work or name

0 references

publication date

10 March 1995

0 references

Journal of Biological Chemistry

0 references

270

0 references

5057-64

0 references

10

0 references

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Retroviral transfer of genes into canine hemopoietic progenitor cells in culture: a model for human gene therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Retrovirus-mediated transfer and expression of drug resistance genes in human haematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Construction of a dominant selectable marker using a novel dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Coupled expression of Ca2+ transport ATPase and a dihydrofolate reductase selectable marker in a mammalian cell system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Transfection with a cDNA encoding a Ser31 or Ser34 mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Systemic resistance to methotrexate in transgenic mice carrying a mutant dihydrofolate reductase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Saturation mutagenesis at dihydrofolate reductase codons 22 and 31. A variety of amino acid substitutions conferring methotrexate resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Critical role of phenylalanine 34 of human dihydrofolate reductase in substrate and inhibitor binding and in catalysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

A program for efficient integration of rate equations and least-squares fitting of chemical reaction data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Determination by Raman spectroscopy of the pKa of N5 of dihydrofolate bound to dihydrofolate reductase: mechanistic implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5057

21 January 2018

Identifiers

10.1074/JBC.270.10.5057

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27730413&oldid=1962515381"