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2 A crystal structure of an extracellular fragment of human CD40 ligand
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title
2 A crystal structure of an extracellular fragment of human CD40 ligand
(English)
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main subject
crystal structure
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author name string
M Karpusas
series ordinal
1
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Y M Hsu
series ordinal
2
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J H Wang
series ordinal
3
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J Thompson
series ordinal
4
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S Lederman
series ordinal
5
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L Chess
series ordinal
6
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D Thomas
series ordinal
7
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publication date
15 October 1995
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published in
Structure
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volume
3
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issue
10
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page(s)
1031-9
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cites work
Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)
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Molecular and biological characterization of a murine ligand for CD40
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A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
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Cloning of TRAP, a ligand for CD40 on human T cells
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Isolation of cDNAs encoding T-BAM, a surface glycoprotein on CD4+ T cells mediating contact-dependent helper function for B cells: identity with the CD40-ligand
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Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion
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Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes
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Mice deficient for the CD40 ligand
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Humoral immune responses in CD40 ligand-deficient mice
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CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome
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Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM
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CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM
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The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome
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Deletions in the ligand for CD40 in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1).
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Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40
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CD40 ligand has potent antiviral activity
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A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors
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Knowledge-based model building of proteins: concepts and examples
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Structure of tumour necrosis factor
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Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation
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Identification of residues on CD40 and its ligand which are critical for the receptor-ligand interaction
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Structure-activity studies of human tumour necrosis factors
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A hot spot of binding energy in a hormone-receptor interface
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The CCP4 suite: programs for protein crystallography
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Solvent content of protein crystals
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Crystallographic R factor refinement by molecular dynamics
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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures
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Identifiers
DOI
10.1016/S0969-2126(01)00239-8
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PubMed ID
8589998
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