(Q27733398)

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The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors

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The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors (English)

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Hydroxysteroid 17-beta dehydrogenase 1

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GOA release 2020-03-11

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GOA release 2020-03-11

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author name string

R Breton

1

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D Housset

2

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C Mazza

3

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J C Fontecilla-Camps

4

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publication date

15 August 1996

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4

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8

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905-15

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8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer

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The relationship between 17 beta-hydroxysteroid dehydrogenase activity and oestrogen concentrations in human breast tumours and in normal breast tissue

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Regulation of 17 beta-hydroxysteroid dehydrogenase in a newly-established human breast carcinoma cell line

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Estrogen synthesis in normal and malignant human endometrium

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Steroidal regulation of oestradiol-17 beta dehydrogenase activity of the human breast cancer cell line MCF-7

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The refined three-dimensional structure of 3 alpha,20 beta-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases

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Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor

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Site-directed mutagenesis of the putative active site of human 17 beta-hydroxysteroid dehydrogenase type 1.

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10.1016/S0969-2126(96)00098-6

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