(Q27740706)

English

Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding

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scholarly article

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Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding (English)

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crystal structure

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author name string

G D Lin

1

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D Chattopadhyay

2

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M Maki

3

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K K Wang

4

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M Carson

5

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L Jin

6

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P W Yuen

7

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E Takano

8

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M Hatanaka

9

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L J DeLucas

10

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S V Narayana

11

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publication date

July 1997

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Nature structural biology

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4

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7

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539-47

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An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

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https://api.crossref.org/works/10.1038/NSB0797-539

20 April 2017

Calcium-dependent proteinase activity in root cultures of Arabidopsis.

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Catalytic-site characteristics of the porcine calpain II 80 kDa/18 kDa heterodimer revealed by selective reaction of its essential thiol group with two-hydronic-state time-dependent inhibitors: evidence for a catalytic site Cys/His interactive syste

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Distinct kinetics of subunit autolysis in mammalian m-calpain activation.

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Ca 2+ -specific removal of Z lines from rabbit skeletal muscle

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Limited proteolytic modification of a neurofilament protein involves a proteinase activated by endogenous levels of calcium.

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Calpain inhibition: an overview of its therapeutic potential

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Calcium binding induces conformational changes in muscle regulatory proteins

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Calcium binding and conformational response in EF-hand proteins

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Preference of calcium-dependent interactions between calmodulin-like domains of calpain and calpastatin subdomains

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Extralysosomal protein degradation

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https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

21 January 2018

Calpain dissociates into subunits in the presence of calcium ions

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Myocardial calpain 2 is inhibited by monoclonal antibodies specific for the small, noncatalytic subunit.

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

A Ca2+ion-activated protease possibly involved in myofibrillar protein turnover. Purification from porcine muscle

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Identification of Ca2+-Activated Neutral Protease in the Peripheral Nerve and Its Effects on Neurofilament Degeneration

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Activation of a calmodulin-dependent phosphatase by a Ca2+-dependent protease

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Inhibition of proteolysis protects hippocampal neurons from ischemia

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Gene structure of calcium-dependent protease retains the ancestral organization of the calcium-binding protein gene

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Carboxyl-terminal truncation and site-directed mutagenesis of the EF hand structure-domain of the small subunit of rabbit calcium-dependent protease

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

EF-hands reach out

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Structure of vitamin D-dependent calcium-binding protein from bovine intestine

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Calcium-induced conformational transition revealed by the solution structure of apo calmodulin

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Solution structure of calcium-free calmodulin

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Calcium-induced structural changes and domain autonomy in calmodulin

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Effect of Ca2+ on the inhibition of calcium-activated neutral protease by leupeptin, antipain and epoxysuccinate derivatives

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Requirement of different subdomains of calpastatin for calpain inhibition and for binding to calmodulin-like domains

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

An assessment of the effect of the helix dipole in protein structures

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

The small subunits of calcium dependent proteases with different calcium sensitivities are identical

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Calcium activated neutral protease--structure-function relationship and functional implications

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https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

The COOH-terminal E-F hand structure of calcium-activated neutral protease (CANP) is important for the association of subunits and resulting proteolytic activity

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1038%2FNSB0797-539

31 March 2020

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10.1038/NSB0797-539

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