(Q27748829)

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Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA

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Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA (English)

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crystal structure

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author name string

F E Chen

1

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D B Huang

2

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Y Q Chen

3

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G Ghosh

4

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language of work or name

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publication date

22 January 1998

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391

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410-3

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6665

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Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Structure, regulation and function of NF-kappa B

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The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

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DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide

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Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control

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Structure of NF-kappa B p50 homodimer bound to a kappa B site

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Structure of the NF-kappa B p50 homodimer bound to DNA

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The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids

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Reversal of intrinsic DNA bends in the IFN beta gene enhancer by transcription factors and the architectural protein HMG I(Y)

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N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-kappa B p50 and p65.

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The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity

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A striking similarity in the organization of the E-selectin and beta interferon gene promoters

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Functionally distinct NF-kappa B binding sites in the immunoglobulin kappa and IL-2 receptor alpha chain genes

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