(Q27765161)

English

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

X-ray crystallography

0 references

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Tomasz Ostrowski

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

author name string

J N Champness

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

M S Bennett

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

R Visse

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

W C Summers

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

E de Clerq

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

R L Jarvest

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

M R Sanderson

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

language of work or name

0 references

publication date

1 August 1998

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

32

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

350-361

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Targeting of an inducible toxic phenotype in animal cells

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

The three-dimensional structure of thymidine kinase from herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Synthesis, Biological Evaluation, and Structure Analysis of a Series of New 1,5-Anhydrohexitol Nucleosides

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Synthesis of 2?-Deoxy-5-(isothiazol-5-yl)uridine and Its Interaction with the HSV-1 Thymidine Kinase

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Synthesis, properties, and pharmacokinetic studies of N2-phenylguanine derivatives as inhibitors of herpes simplex virus thymidine kinases

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Prediction of the binding mode of N2-phenylguanine derivative inhibitors to herpes simplex virus type 1 thymidine kinase

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Purification and crystallization of thymidine kinase from herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Crystallographic R factor refinement by molecular dynamics

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Use of isotopically chiral [4'-13C]penciclovir and 13C NMR to determine the specificity and absolute configuration of penciclovir phosphate esters formed in HSV-1 and HSV-2 infected cells and by HSV-1-encoded thymidine kinase

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819980815%2932%3A3%3C350%3A%3AAID-PROT10%3E3.0.CO%3B2-8

21 January 2018

Identifiers

10.1002/(SICI)1097-0134(19980815)32:3<350::AID-PROT10>3.0.CO;2-8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9715911%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27765161&oldid=1568367117"