(Q27765344)

English

Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state

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Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state (English)

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crystal structure

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author name string

R Dominguez

1

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Y Freyzon

2

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K M Trybus

3

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C Cohen

4

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language of work or name

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publication date

4 September 1998

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94

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5

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559-71

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Tertiary structural changes in the cleft containing the ATP sensitive tryptophan and reactive thiol are consistent with pivoting of the myosin heavy chain at Gly699.

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X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-

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Structural studies on myosin II: communication between distant protein domains

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X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain

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Substitution mutations in the myosin essential light chain lead to reduced actin-activated ATPase activity despite stoichiometric binding to the heavy chain

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Muscle proteins--their actions and interactions

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The swinging lever-arm hypothesis of muscle contraction.

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Flexibility of the myosin heavy chain: direct evidence that the region containing SH1 and SH2 can move 10 A under the influence of nucleotide binding

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Cold-sensitive mutants G680V and G691C of Dictyostelium myosin II confer dramatically different biochemical defects

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