(Q27863900)

English

Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.

scientific article

Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1

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scholarly article

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15 November 2016

Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1. (English)

1 reference

15 November 2016

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structural biology

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author name string

Young Ho Kim

1

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Yongsok Kim

6

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Yong-Ou Kim

4

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Sook-Jeong Lee

3

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Ki Sa Sung

2

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Cheol Yong Choi

5

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language of work or name

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publication date

7 November 2005

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1 reference

579

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27

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6272-8

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Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

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The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription

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Phosphorylation by the DHIPK2 protein kinase modulates the corepressor activity of Groucho

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Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

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Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

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Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

1 reference

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Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1

1 reference

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Differential interactions of the homeodomain-interacting protein kinase 2 (HIPK2) by phosphorylation-dependent sumoylation

1 reference

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Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability.

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The homeodomain-interacting kinase PKM (HIPK-2) modifies ND10 through both its kinase domain and a SUMO-1 interaction motif and alters the posttranslational modification of PML.

1 reference

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SUMO: a history of modification

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Protein modification by SUMO

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Versatile protein tag, SUMO: its enzymology and biological function

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A new protease required for cell-cycle progression in yeast

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Differential regulation of sentrinized proteins by a novel sentrin-specific protease

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Ubiquitin-like proteins: new wines in new bottles

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The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein

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Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins

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Characterization of the Localization and Proteolytic Activity of the SUMO-specific Protease, SENP1

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A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs

1 reference

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A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase

1 reference

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Association of the human SUMO-1 protease SENP2 with the nuclear pore

1 reference

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Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation

1 reference

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SUMO-1 protease-1 regulates gene transcription through PML

1 reference

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Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis

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Salivary gland determination in Drosophila: a salivary-specific, fork head enhancer integrates spatial pattern and allows fork head autoregulation

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Nuclear bodies and compartments: functional roles and cellular signalling in health and disease

1 reference

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PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

1 reference

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Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification

1 reference

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SUMO-1 modification required for transformation by adenovirus type 5 early region 1B 55-kDa oncoprotein

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Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation

1 reference

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SUMO protein modification.

1 reference

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21 January 2018

Identifiers

10.1016/J.FEBSLET.2005.10.010

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15 November 2016

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